WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000029639 TFB1M ENSG00000165392 WRN H. sapiens SDL Slorth 0.915568 View
ENSG00000165392 WRN ENSG00000165806 CASP7 H. sapiens SDL Slorth 0.915344 View
ENSG00000123612 ACVR1C ENSG00000165392 WRN H. sapiens SDL Slorth 0.915293 View
ENSG00000156345 CDK20 ENSG00000165392 WRN H. sapiens SDL Slorth 0.91509 View
ENSG00000063660 GPC1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.915068 View
ENSG00000041982 TNC ENSG00000165392 WRN H. sapiens SDL Slorth 0.915068 View
ENSG00000160360 GPSM1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.915051 View
ENSG00000145331 TRMT10A ENSG00000165392 WRN H. sapiens SDL Slorth 0.91502 View
ENSG00000165392 WRN ENSG00000169756 LIMS1 H. sapiens SDL Slorth 0.914886 View
ENSG00000114302 PRKAR2A ENSG00000165392 WRN H. sapiens SSL Slorth 0.914839 View
ENSG00000165392 WRN ENSG00000197728 RPS26 H. sapiens SDL Slorth 0.914713 View
ENSG00000136504 KAT7 ENSG00000165392 WRN H. sapiens SDL Slorth 0.914684 View
ENSG00000108773 KAT2A ENSG00000165392 WRN H. sapiens SDL Slorth 0.914467 View
ENSG00000111218 PRMT8 ENSG00000165392 WRN H. sapiens SDL Slorth 0.914259 View
ENSG00000149480 MTA2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.914211 View
ENSG00000072803 FBXW11 ENSG00000165392 WRN H. sapiens SSL Slorth 0.91415 View
ENSG00000114767 RRP9 ENSG00000165392 WRN H. sapiens SSL Slorth 0.914117 View
ENSG00000102034 ELF4 ENSG00000165392 WRN H. sapiens SDL Slorth 0.9141 View
ENSG00000144034 TPRKB ENSG00000165392 WRN H. sapiens SDL Slorth 0.913952 View
ENSG00000078114 NEBL ENSG00000165392 WRN H. sapiens SDL Slorth 0.913509 View
ENSG00000165392 WRN ENSG00000186575 NF2 H. sapiens SSL Slorth 0.913263 View
ENSG00000141503 MINK1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.913222 View
ENSG00000130382 MLLT1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.913208 View
ENSG00000165392 WRN ENSG00000169139 UBE2V2 H. sapiens SDL Slorth 0.913154 View
ENSG00000165392 WRN ENSG00000174013 FBXO45 H. sapiens SDL Slorth 0.913033 View
ENSG00000165392 WRN ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.912983 View
ENSG00000112062 MAPK14 ENSG00000165392 WRN H. sapiens SDL Slorth 0.912777 View
ENSG00000133316 WDR74 ENSG00000165392 WRN H. sapiens SSL Slorth 0.912732 View
ENSG00000074266 EED ENSG00000165392 WRN H. sapiens SSL Slorth 0.912637 View
ENSG00000096384 HSP90AB1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.912637 View
ENSG00000165392 WRN ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.912449 View
ENSG00000165392 WRN ENSG00000166167 BTRC H. sapiens SSL Slorth 0.912441 View
ENSG00000100138 SNU13 ENSG00000165392 WRN H. sapiens SDL Slorth 0.912391 View
ENSG00000165392 WRN ENSG00000181788 SIAH2 H. sapiens SDL Slorth 0.912304 View
ENSG00000165392 WRN ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.912279 View
ENSG00000165392 WRN ENSG00000171848 RRM2 H. sapiens SDL Slorth 0.912157 View
ENSG00000138814 PPP3CA ENSG00000165392 WRN H. sapiens SSL Slorth 0.912146 View
ENSG00000165392 WRN ENSG00000273841 TAF9 H. sapiens SSL Slorth 0.912145 View
ENSG00000165115 KIF27 ENSG00000165392 WRN H. sapiens SDL Slorth 0.912039 View
ENSG00000070404 FSTL3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.911922 View