PRMT8 - WRN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRMT8	ENSG00000111218	No diseases in record	No drugs in record	protein binding histone-arginine N-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity identical protein binding protein homodimerization activity protein heterodimerization activity	HMT1 (S. cerevisiae) prmt-1 (C. elegans) Art1 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)