WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000165392 WRN ENSG00000188130 MAPK12 H. sapiens SDL Slorth 0.930802 View
ENSG00000165392 WRN ENSG00000254087 LYN H. sapiens SSL Slorth 0.930718 View
ENSG00000112118 MCM3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.930705 View
ENSG00000099817 POLR2E ENSG00000165392 WRN H. sapiens SSL Slorth 0.930595 View
ENSG00000090889 KIF4A ENSG00000165392 WRN H. sapiens SDL Slorth 0.930566 View
ENSG00000095002 MSH2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.930546 View
ENSG00000113558 SKP1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.930497 View
ENSG00000158092 NCK1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.930469 View
ENSG00000101966 XIAP ENSG00000165392 WRN H. sapiens SDL Slorth 0.930318 View
ENSG00000104365 IKBKB ENSG00000165392 WRN H. sapiens SSL Slorth 0.930276 View
ENSG00000165392 WRN ENSG00000170004 CHD3 H. sapiens SDL Slorth 0.930275 View
ENSG00000109971 HSPA8 ENSG00000165392 WRN H. sapiens SDL Slorth 0.930267 View
ENSG00000068024 HDAC4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.930055 View
ENSG00000114315 HES1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.929965 View
ENSG00000161940 BCL6B ENSG00000165392 WRN H. sapiens SDL Slorth 0.929847 View
ENSG00000085832 EPS15 ENSG00000165392 WRN H. sapiens SSL Slorth 0.92983 View
ENSG00000100852 ARHGAP5 ENSG00000165392 WRN H. sapiens SDL Slorth 0.929671 View
ENSG00000135723 FHOD1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.929482 View
ENSG00000016082 ISL1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.929022 View
ENSG00000165392 WRN ENSG00000197122 SRC H. sapiens SSL Slorth 0.928834 View
ENSG00000123600 METTL8 ENSG00000165392 WRN H. sapiens SDL Slorth 0.928813 View
ENSG00000138756 BMP2K ENSG00000165392 WRN H. sapiens SDL Slorth 0.928793 View
ENSG00000139618 BRCA2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.928767 View
ENSG00000136937 NCBP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.928668 View
ENSG00000072163 LIMS2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.928501 View
ENSG00000087510 TFAP2C ENSG00000165392 WRN H. sapiens SDL Slorth 0.928434 View
ENSG00000132341 RAN ENSG00000165392 WRN H. sapiens SDL Slorth 0.92839 View
ENSG00000165392 WRN ENSG00000172071 EIF2AK3 H. sapiens SDL Slorth 0.928316 View
ENSG00000077092 RARB ENSG00000165392 WRN H. sapiens SDL Slorth 0.928287 View
ENSG00000110395 CBL ENSG00000165392 WRN H. sapiens SDL Slorth 0.928234 View
ENSG00000165392 WRN ENSG00000169891 REPS2 H. sapiens SDL Slorth 0.927923 View
ENSG00000136237 RAPGEF5 ENSG00000165392 WRN H. sapiens SDL Slorth 0.927917 View
ENSG00000067141 NEO1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.927841 View
ENSG00000105204 DYRK1B ENSG00000165392 WRN H. sapiens SDL Slorth 0.927836 View
ENSG00000058404 CAMK2B ENSG00000165392 WRN H. sapiens SDL Slorth 0.927697 View
ENSG00000118900 UBN1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.927649 View
ENSG00000102145 GATA1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.927649 View
ENSG00000165392 WRN ENSG00000170315 UBB H. sapiens SSL Slorth 0.927293 View
ENSG00000125740 FOSB ENSG00000165392 WRN H. sapiens SDL Slorth 0.927119 View
ENSG00000165392 WRN ENSG00000169083 AR H. sapiens SSL Slorth 0.927008 View