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Slorth
NCK1 - WRN
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
NCK1
ENSG00000158092
No diseases in record
No drugs in record
protein kinase inhibitor activity
SH3/SH2 adaptor activity
ARF guanyl-nucleotide exchange factor activity
receptor binding
protein binding
cytoskeletal adaptor activity
protein domain specific binding
receptor signaling complex scaffold activity
protein binding, bridging
receptor tyrosine kinase binding
ephrin receptor binding
eukaryotic initiation factor eIF2 binding
cadherin binding involved in cell-cell adhesion
nck-1 (C. elegans)
dock (D. melanogaster)
WRN
ENSG00000165392
osteosarcoma
meningioma
other tumour types
No drugs in record
magnesium ion binding
Y-form DNA binding
bubble DNA binding
DNA binding
DNA helicase activity
chromatin binding
ATP-dependent DNA helicase activity
helicase activity
exonuclease activity
protein binding
ATP binding
3'-5' exonuclease activity
four-way junction helicase activity
ATPase activity
manganese ion binding
protein complex binding
protein homodimerization activity
3'-5' DNA helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
SGS1 (S. cerevisiae)
wrn-1 (C. elegans)