WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000115808 STRN ENSG00000165392 WRN H. sapiens SSL Slorth 0.933654 View
ENSG00000127329 PTPRB ENSG00000165392 WRN H. sapiens SDL Slorth 0.933573 View
ENSG00000138829 FBN2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.933573 View
ENSG00000134871 COL4A2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.933573 View
ENSG00000136492 BRIP1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.933458 View
ENSG00000105011 ASF1B ENSG00000165392 WRN H. sapiens SSL Slorth 0.933398 View
ENSG00000005007 UPF1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.933293 View
ENSG00000164924 YWHAZ ENSG00000165392 WRN H. sapiens SDL Slorth 0.933274 View
ENSG00000103197 TSC2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.933259 View
ENSG00000165392 WRN ENSG00000198517 MAFK H. sapiens SDL Slorth 0.933105 View
ENSG00000135597 REPS1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.933021 View
ENSG00000078043 PIAS2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.932993 View
ENSG00000165392 WRN ENSG00000168421 RHOH H. sapiens SDL Slorth 0.932833 View
ENSG00000165392 WRN ENSG00000172732 MUS81 H. sapiens SDL Slorth 0.932751 View
ENSG00000165392 WRN ENSG00000169372 CRADD H. sapiens SDL Slorth 0.932748 View
ENSG00000079102 RUNX1T1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.932746 View
ENSG00000117713 ARID1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.932589 View
ENSG00000163558 PRKCI ENSG00000165392 WRN H. sapiens SSL Slorth 0.932549 View
ENSG00000160193 WDR4 ENSG00000165392 WRN H. sapiens SDL Slorth 0.932503 View
ENSG00000124164 VAPB ENSG00000165392 WRN H. sapiens SSL Slorth 0.932376 View
ENSG00000110107 PRPF19 ENSG00000165392 WRN H. sapiens SSL Slorth 0.932285 View
ENSG00000115694 STK25 ENSG00000165392 WRN H. sapiens SSL Slorth 0.932081 View
ENSG00000116017 ARID3A ENSG00000165392 WRN H. sapiens SDL Slorth 0.932043 View
ENSG00000095015 MAP3K1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.931871 View
ENSG00000126457 PRMT1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.931869 View
ENSG00000165392 WRN ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.931818 View
ENSG00000132326 PER2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.931767 View
ENSG00000144554 FANCD2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.931697 View
ENSG00000066468 FGFR2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.93167 View
ENSG00000104375 STK3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.931634 View
ENSG00000165392 WRN ENSG00000197157 SND1 H. sapiens SDL Slorth 0.931603 View
ENSG00000006451 RALA ENSG00000165392 WRN H. sapiens SSL Slorth 0.931466 View
ENSG00000165392 WRN ENSG00000166341 DCHS1 H. sapiens SDL Slorth 0.931353 View
ENSG00000149923 PPP4C ENSG00000165392 WRN H. sapiens SSL Slorth 0.931343 View
ENSG00000085840 ORC1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.931298 View
ENSG00000165392 WRN ENSG00000178573 MAF H. sapiens SDL Slorth 0.931277 View
ENSG00000145358 DDIT4L ENSG00000165392 WRN H. sapiens SDL Slorth 0.93103 View
ENSG00000132466 ANKRD17 ENSG00000165392 WRN H. sapiens SDL Slorth 0.930918 View
ENSG00000121022 COPS5 ENSG00000165392 WRN H. sapiens SDL Slorth 0.930886 View
ENSG00000049323 LTBP1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.930879 View