WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000114166 KAT2B ENSG00000165392 WRN H. sapiens SSL Slorth 0.947707 View
ENSG00000036257 CUL3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.947573 View
ENSG00000067606 PRKCZ ENSG00000165392 WRN H. sapiens SSL Slorth 0.947479 View
ENSG00000125952 MAX ENSG00000165392 WRN H. sapiens SSL Slorth 0.947478 View
ENSG00000093009 CDC45 ENSG00000165392 WRN H. sapiens SSL Slorth 0.947469 View
ENSG00000162231 NXF1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.947445 View
ENSG00000139842 CUL4A ENSG00000165392 WRN H. sapiens SSL Slorth 0.947392 View
ENSG00000110395 CBL ENSG00000165392 WRN H. sapiens SSL Slorth 0.947168 View
ENSG00000148835 TAF5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.947149 View
ENSG00000137073 UBAP2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.946979 View
ENSG00000128739 SNRPN ENSG00000165392 WRN H. sapiens SSL Slorth 0.946843 View
ENSG00000129691 ASH2L ENSG00000165392 WRN H. sapiens SSL Slorth 0.946799 View
ENSG00000102054 RBBP7 ENSG00000165392 WRN H. sapiens SSL Slorth 0.946761 View
ENSG00000115942 ORC2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.946668 View
ENSG00000165392 WRN ENSG00000170734 POLH H. sapiens SDL Slorth 0.946355 View
ENSG00000120500 ARR3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.945969 View
ENSG00000118689 FOXO3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.945913 View
ENSG00000165392 WRN ENSG00000169375 SIN3A H. sapiens SSL Slorth 0.945713 View
ENSG00000071051 NCK2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.945645 View
ENSG00000165392 WRN ENSG00000178295 GEN1 H. sapiens SDL Slorth 0.945617 View
ENSG00000004487 KDM1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.945553 View
ENSG00000136238 RAC1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.945428 View
ENSG00000165392 WRN ENSG00000168646 AXIN2 H. sapiens SDL Slorth 0.945353 View
ENSG00000108840 HDAC5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.94531 View
ENSG00000127586 CHTF18 ENSG00000165392 WRN H. sapiens SSL Slorth 0.945228 View
ENSG00000106346 USP42 ENSG00000165392 WRN H. sapiens SDL Slorth 0.945075 View
ENSG00000113712 CSNK1A1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.945071 View
ENSG00000092201 SUPT16H ENSG00000165392 WRN H. sapiens SSL Slorth 0.944889 View
ENSG00000090372 STRN4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.944885 View
ENSG00000165392 WRN ENSG00000170315 UBB H. sapiens SDL Slorth 0.944875 View
ENSG00000165392 WRN ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.944795 View
ENSG00000165392 WRN ENSG00000197299 BLM H. sapiens SDL Slorth 0.944692 View
ENSG00000165392 WRN ENSG00000168283 BMI1 H. sapiens SSL Slorth 0.944674 View
ENSG00000165392 WRN ENSG00000186575 NF2 H. sapiens SDL Slorth 0.94467 View
ENSG00000146094 DOK3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.94456 View
ENSG00000157601 MX1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.94455 View
ENSG00000165392 WRN ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.944539 View
ENSG00000147536 GINS4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.944485 View
ENSG00000163485 ADORA1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.944444 View
ENSG00000103479 RBL2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.944375 View