WRN - GEN1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
WRN ENSG00000165392 osteosarcoma
meningioma
other tumour types

No drugs in record

magnesium ion binding
Y-form DNA binding
bubble DNA binding
DNA binding
DNA helicase activity
chromatin binding
ATP-dependent DNA helicase activity
helicase activity
exonuclease activity
protein binding
ATP binding
3'-5' exonuclease activity
four-way junction helicase activity
ATPase activity
manganese ion binding
protein complex binding
protein homodimerization activity
3'-5' DNA helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
SGS1 (S. cerevisiae)
wrn-1 (C. elegans)
GEN1 ENSG00000178295

No diseases in record

No drugs in record

DNA binding
endodeoxyribonuclease activity
crossover junction endodeoxyribonuclease activity
metal ion binding
RAD27 (S. cerevisiae)
crn-1 (C. elegans)
Gen (D. melanogaster)