WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000150459 SAP18 ENSG00000165392 WRN H. sapiens SSL Slorth 0.958414 View
ENSG00000123200 ZC3H13 ENSG00000165392 WRN H. sapiens SSL Slorth 0.958343 View
ENSG00000072062 PRKACA ENSG00000165392 WRN H. sapiens SSL Slorth 0.958247 View
ENSG00000165392 WRN ENSG00000184900 SUMO3 H. sapiens SDL Slorth 0.958189 View
ENSG00000116044 NFE2L2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.957946 View
ENSG00000102317 RBM3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.957936 View
ENSG00000117748 RPA2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.957911 View
ENSG00000118260 CREB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.957894 View
ENSG00000164885 CDK5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.95777 View
ENSG00000165392 WRN ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.957703 View
ENSG00000165392 WRN ENSG00000168610 STAT3 H. sapiens SSL Slorth 0.957588 View
ENSG00000164305 CASP3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.957521 View
ENSG00000165392 WRN ENSG00000177981 ASB8 H. sapiens SDL Slorth 0.957499 View
ENSG00000165392 WRN ENSG00000170365 SMAD1 H. sapiens SSL Slorth 0.957438 View
ENSG00000165392 WRN ENSG00000187098 MITF H. sapiens SDL Slorth 0.957344 View
ENSG00000096384 HSP90AB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.957341 View
ENSG00000165392 WRN ENSG00000182511 FES H. sapiens SDL Slorth 0.95733 View
ENSG00000141564 RPTOR ENSG00000165392 WRN H. sapiens SSL Slorth 0.957307 View
ENSG00000165392 WRN ENSG00000168283 BMI1 H. sapiens SDL Slorth 0.957173 View
ENSG00000165392 WRN ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.957037 View
ENSG00000133101 CCNA1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.956961 View
ENSG00000165025 SYK ENSG00000165392 WRN H. sapiens SSL Slorth 0.956826 View
ENSG00000100029 PES1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.956811 View
ENSG00000154473 BUB3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.95671 View
ENSG00000150093 ITGB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.956688 View
ENSG00000137154 RPS6 ENSG00000165392 WRN H. sapiens SDL Slorth 0.956507 View
ENSG00000165392 WRN ENSG00000175643 RMI2 H. sapiens SDL Slorth 0.956494 View
ENSG00000165392 WRN ENSG00000175054 ATR H. sapiens SSL Slorth 0.956445 View
ENSG00000062822 POLD1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.956425 View
ENSG00000165392 WRN ENSG00000198911 SREBF2 H. sapiens SDL Slorth 0.956176 View
ENSG00000141480 ARRB2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.95617 View
ENSG00000165392 WRN ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.95611 View
ENSG00000148400 NOTCH1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.956009 View
ENSG00000067829 IDH3G ENSG00000165392 WRN H. sapiens SDL Slorth 0.955965 View
ENSG00000100644 HIF1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.955842 View
ENSG00000149311 ATM ENSG00000165392 WRN H. sapiens SDL Slorth 0.955817 View
ENSG00000136875 PRPF4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.955789 View
ENSG00000139687 RB1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.955758 View
ENSG00000165392 WRN ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.955495 View
ENSG00000073969 NSF ENSG00000165392 WRN H. sapiens SSL Slorth 0.955367 View