WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000004700 RECQL ENSG00000165392 WRN H. sapiens SSL Slorth 0.96424 View
ENSG00000165392 WRN ENSG00000177889 UBE2N H. sapiens SSL Slorth 0.964084 View
ENSG00000165392 WRN ENSG00000196419 XRCC6 H. sapiens SDL Slorth 0.964036 View
ENSG00000141736 ERBB2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.964003 View
ENSG00000123124 WWP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.963977 View
ENSG00000165392 WRN ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.963974 View
ENSG00000165392 WRN ENSG00000169800 RBMY1F H. sapiens SDL Slorth 0.963939 View
ENSG00000134057 CCNB1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.963909 View
ENSG00000124181 PLCG1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.9639 View
ENSG00000165392 WRN ENSG00000221829 FANCG H. sapiens SDL Slorth 0.96381 View
ENSG00000096717 SIRT1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.963777 View
ENSG00000134086 VHL ENSG00000165392 WRN H. sapiens SSL Slorth 0.963566 View
ENSG00000124762 CDKN1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.963534 View
ENSG00000165392 WRN ENSG00000172977 KAT5 H. sapiens SSL Slorth 0.963522 View
ENSG00000165392 WRN ENSG00000185022 MAFF H. sapiens SDL Slorth 0.963389 View
ENSG00000165392 WRN ENSG00000204103 MAFB H. sapiens SDL Slorth 0.963166 View
ENSG00000132341 RAN ENSG00000165392 WRN H. sapiens SSL Slorth 0.963139 View
ENSG00000072401 UBE2D1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.963084 View
ENSG00000139687 RB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.963055 View
ENSG00000163932 PRKCD ENSG00000165392 WRN H. sapiens SSL Slorth 0.962995 View
ENSG00000130726 TRIM28 ENSG00000165392 WRN H. sapiens SSL Slorth 0.962983 View
ENSG00000165392 WRN ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.962983 View
ENSG00000147010 SH3KBP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.962779 View
ENSG00000154229 PRKCA ENSG00000165392 WRN H. sapiens SSL Slorth 0.962752 View
ENSG00000070010 UFD1L ENSG00000165392 WRN H. sapiens SSL Slorth 0.962618 View
ENSG00000165392 WRN ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.962497 View
ENSG00000165392 WRN ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.962397 View
ENSG00000141027 NCOR1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.962373 View
ENSG00000055332 EIF2AK2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.962304 View
ENSG00000132155 RAF1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.962137 View
ENSG00000104738 MCM4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.962051 View
ENSG00000165392 WRN ENSG00000184937 WT1 H. sapiens SDL Slorth 0.962034 View
ENSG00000145604 SKP2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.962031 View
ENSG00000165392 WRN ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.961949 View
ENSG00000105810 CDK6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.961666 View
ENSG00000128245 YWHAH ENSG00000165392 WRN H. sapiens SSL Slorth 0.961613 View
ENSG00000047315 POLR2B ENSG00000165392 WRN H. sapiens SSL Slorth 0.961481 View
ENSG00000096968 JAK2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.961433 View
ENSG00000157106 SMG1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.961363 View
ENSG00000108424 KPNB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.961331 View