WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000165392 WRN ENSG00000183684 ALYREF H. sapiens SDL Slorth 0.906909 View
ENSG00000112658 SRF ENSG00000165392 WRN H. sapiens SSL Slorth 0.906615 View
ENSG00000139197 PEX5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.906608 View
ENSG00000162236 STX5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.906466 View
ENSG00000145216 FIP1L1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.906341 View
ENSG00000160075 SSU72 ENSG00000165392 WRN H. sapiens SSL Slorth 0.906315 View
ENSG00000165392 WRN ENSG00000173473 SMARCC1 H. sapiens SSL Slorth 0.906281 View
ENSG00000165392 WRN ENSG00000183765 CHEK2 H. sapiens SSL Slorth 0.906232 View
ENSG00000149136 SSRP1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.906164 View
ENSG00000165392 WRN ENSG00000187555 USP7 H. sapiens SSL Slorth 0.90604 View
ENSG00000048462 TNFRSF17 ENSG00000165392 WRN H. sapiens SDL Slorth 0.905747 View
ENSG00000127022 CANX ENSG00000165392 WRN H. sapiens SSL Slorth 0.905732 View
ENSG00000165392 WRN ENSG00000172175 MALT1 H. sapiens SDL Slorth 0.905694 View
ENSG00000134363 FST ENSG00000165392 WRN H. sapiens SDL Slorth 0.905571 View
ENSG00000113013 HSPA9 ENSG00000165392 WRN H. sapiens SSL Slorth 0.905564 View
ENSG00000137693 YAP1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.905227 View
ENSG00000110713 NUP98 ENSG00000165392 WRN H. sapiens SSL Slorth 0.905198 View
ENSG00000165392 WRN ENSG00000187608 ISG15 H. sapiens SSL Slorth 0.905157 View
ENSG00000049759 NEDD4L ENSG00000165392 WRN H. sapiens SSL Slorth 0.905106 View
ENSG00000093009 CDC45 ENSG00000165392 WRN H. sapiens SDL Slorth 0.905086 View
ENSG00000134438 RAX ENSG00000165392 WRN H. sapiens SDL Slorth 0.905052 View
ENSG00000165392 WRN ENSG00000169375 SIN3A H. sapiens SDL Slorth 0.90501 View
ENSG00000165392 WRN ENSG00000167815 PRDX2 H. sapiens SDL Slorth 0.904858 View
ENSG00000115942 ORC2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.904739 View
ENSG00000108883 EFTUD2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.904683 View
ENSG00000165392 WRN ENSG00000198668 CALM1 H. sapiens SDL Slorth 0.904617 View
ENSG00000120837 NFYB ENSG00000165392 WRN H. sapiens SSL Slorth 0.904542 View
ENSG00000165392 WRN ENSG00000213639 PPP1CB H. sapiens SDL Slorth 0.904369 View
ENSG00000135250 SRPK2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.904313 View
ENSG00000131941 RHPN2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.904288 View
ENSG00000122565 CBX3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.904226 View
ENSG00000165392 WRN ENSG00000165806 CASP7 H. sapiens SSL Slorth 0.904141 View
ENSG00000165392 WRN ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.904033 View
ENSG00000076344 RGS11 ENSG00000165392 WRN H. sapiens SDL Slorth 0.903981 View
ENSG00000079387 SENP1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.903798 View
ENSG00000106070 GRB10 ENSG00000165392 WRN H. sapiens SSL Slorth 0.903774 View
ENSG00000165392 WRN ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.903709 View
ENSG00000165392 WRN ENSG00000183765 CHEK2 H. sapiens SDL Slorth 0.903543 View
ENSG00000143420 ENSA ENSG00000165392 WRN H. sapiens SDL Slorth 0.90351 View
ENSG00000131759 RARA ENSG00000165392 WRN H. sapiens SDL Slorth 0.903504 View