WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000165392 WRN ENSG00000198625 MDM4 H. sapiens SSL Slorth 0.903451 View
ENSG00000055130 CUL1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.90342 View
ENSG00000165392 WRN ENSG00000198677 TTC37 H. sapiens SDL Slorth 0.903287 View
ENSG00000165392 WRN ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.903139 View
ENSG00000132170 PPARG ENSG00000165392 WRN H. sapiens SSL Slorth 0.902915 View
ENSG00000165392 WRN ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.902777 View
ENSG00000123094 RASSF8 ENSG00000165392 WRN H. sapiens SDL Slorth 0.902731 View
ENSG00000165392 WRN ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.902321 View
ENSG00000103653 CSK ENSG00000165392 WRN H. sapiens SSL Slorth 0.902258 View
ENSG00000165392 WRN ENSG00000283094 PTEN H. sapiens SDL Slorth 0.901972 View
ENSG00000073584 SMARCE1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.901833 View
ENSG00000115221 ITGB6 ENSG00000165392 WRN H. sapiens SDL Slorth 0.901724 View
ENSG00000147133 TAF1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.901591 View
ENSG00000119335 SET ENSG00000165392 WRN H. sapiens SSL Slorth 0.901494 View
ENSG00000164362 TERT ENSG00000165392 WRN H. sapiens SDL Slorth 0.901429 View
ENSG00000072310 SREBF1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.901199 View
ENSG00000130396 AFDN ENSG00000165392 WRN H. sapiens SSL Slorth 0.901051 View
ENSG00000101109 STK4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.90104 View
ENSG00000138069 RAB1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.900808 View
ENSG00000145375 SPATA5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.900734 View
ENSG00000143776 CDC42BPA ENSG00000165392 WRN H. sapiens SDL Slorth 0.900644 View
ENSG00000101349 PAK5 ENSG00000165392 WRN H. sapiens SDL Slorth 0.900644 View
ENSG00000163536 SERPINI1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.900403 View
ENSG00000152578 GRIA4 ENSG00000165392 WRN H. sapiens SDL Slorth 0.900403 View
ENSG00000101868 POLA1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.900333 View
ENSG00000077097 TOP2B ENSG00000165392 WRN H. sapiens SSL Slorth 0.900306 View
ENSG00000165392 WRN ENSG00000204435 CSNK2B H. sapiens SDL Slorth 0.90016 View
ENSG00000110107 PRPF19 ENSG00000165392 WRN H. sapiens SDL Slorth 0.900069 View
ENSG00000116039 ATP6V1B1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.899485 View
ENSG00000100554 ATP6V1D ENSG00000165392 WRN H. sapiens SSL Slorth 0.899279 View
ENSG00000152818 UTRN ENSG00000165392 WRN H. sapiens SSL Slorth 0.898993 View
ENSG00000130811 EIF3G ENSG00000165392 WRN H. sapiens SSL Slorth 0.89896 View
ENSG00000065427 KARS ENSG00000165392 WRN H. sapiens SSL Slorth 0.89864 View
ENSG00000112576 CCND3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.89836 View
ENSG00000100028 SNRPD3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.898263 View
ENSG00000164109 MAD2L1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.898154 View
ENSG00000164941 INTS8 ENSG00000165392 WRN H. sapiens SSL Slorth 0.898016 View
ENSG00000072518 MARK2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.897884 View
ENSG00000085733 CTTN ENSG00000165392 WRN H. sapiens SSL Slorth 0.896766 View
ENSG00000151090 THRB ENSG00000165392 WRN H. sapiens SSL Slorth 0.89659 View