WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000033327 GAB2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.876857 View
ENSG00000114742 WDR48 ENSG00000165392 WRN H. sapiens SSL Slorth 0.876696 View
ENSG00000134058 CDK7 ENSG00000165392 WRN H. sapiens SSL Slorth 0.875653 View
ENSG00000067560 RHOA ENSG00000165392 WRN H. sapiens SSL Slorth 0.875352 View
ENSG00000075711 DLG1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.874522 View
ENSG00000133119 RFC3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.874124 View
ENSG00000122566 HNRNPA2B1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.873912 View
ENSG00000108953 YWHAE ENSG00000165392 WRN H. sapiens SSL Slorth 0.873791 View
ENSG00000165392 WRN ENSG00000175793 SFN H. sapiens SSL Slorth 0.873513 View
ENSG00000033800 PIAS1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.873501 View
ENSG00000165392 WRN ENSG00000198087 CD2AP H. sapiens SSL Slorth 0.873468 View
ENSG00000144231 POLR2D ENSG00000165392 WRN H. sapiens SSL Slorth 0.872899 View
ENSG00000111859 NEDD9 ENSG00000165392 WRN H. sapiens SSL Slorth 0.872769 View
ENSG00000138071 ACTR2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.872294 View
ENSG00000108262 GIT1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.871821 View
ENSG00000137413 TAF8 ENSG00000165392 WRN H. sapiens SSL Slorth 0.871392 View
ENSG00000165392 WRN ENSG00000171824 EXOSC10 H. sapiens SSL Slorth 0.871259 View
ENSG00000103769 RAB11A ENSG00000165392 WRN H. sapiens SSL Slorth 0.871068 View
ENSG00000096401 CDC5L ENSG00000165392 WRN H. sapiens SSL Slorth 0.871029 View
ENSG00000163110 PDLIM5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.870932 View
ENSG00000150995 ITPR1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.870897 View
ENSG00000121653 MAPK8IP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.870854 View
ENSG00000142655 PEX14 ENSG00000165392 WRN H. sapiens SSL Slorth 0.870818 View
ENSG00000126524 SBDS ENSG00000165392 WRN H. sapiens SSL Slorth 0.870761 View
ENSG00000108590 MED31 ENSG00000165392 WRN H. sapiens SSL Slorth 0.870549 View
ENSG00000019995 ZRANB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.870426 View
ENSG00000165392 WRN ENSG00000198561 CTNND1 H. sapiens SSL Slorth 0.870107 View
ENSG00000165392 WRN ENSG00000165731 RET H. sapiens SSL Slorth 0.869852 View
ENSG00000150457 LATS2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.869693 View
ENSG00000079277 MKNK1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.869512 View
ENSG00000134440 NARS ENSG00000165392 WRN H. sapiens SSL Slorth 0.869147 View
ENSG00000069399 BCL3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.868959 View
ENSG00000140443 IGF1R ENSG00000165392 WRN H. sapiens SSL Slorth 0.868736 View
ENSG00000165392 WRN ENSG00000176890 TYMS H. sapiens SSL Slorth 0.868135 View
ENSG00000159461 AMFR ENSG00000165392 WRN H. sapiens SSL Slorth 0.867797 View
ENSG00000123159 GIPC1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.867742 View
ENSG00000101367 MAPRE1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.867205 View
ENSG00000115524 SF3B1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.866351 View
ENSG00000115053 NCL ENSG00000165392 WRN H. sapiens SSL Slorth 0.8653 View
ENSG00000088832 FKBP1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.865154 View