POLR2D - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLR2D	ENSG00000144231	No diseases in record	No drugs in record	nucleotide binding DNA-directed 5'-3' RNA polymerase activity translation initiation factor binding single-stranded DNA binding single-stranded RNA binding	RPB4 (S. cerevisiae) rpb-4 (C. elegans) Rpb4 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)