YWHAE - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
YWHAE	ENSG00000108953	endometrial stromal sarcoma	No drugs in record	protein binding potassium channel regulator activity enzyme binding protein domain specific binding MHC class II protein complex binding ubiquitin protein ligase binding histone deacetylase binding ion channel binding protein heterodimerization activity phosphoserine residue binding phosphoprotein binding cadherin binding involved in cell-cell adhesion	BMH1 (S. cerevisiae) BMH2 (S. cerevisiae) M117.3 (C. elegans) 14-3-3epsilon (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)