PIN1 - WRN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIN1	ENSG00000127445	No diseases in record	No drugs in record	peptidyl-prolyl cis-trans isomerase activity motor activity protein binding beta-catenin binding mitogen-activated protein kinase kinase binding GTPase activating protein binding phosphoserine residue binding phosphothreonine residue binding	ESS1 (S. cerevisiae) dod (D. melanogaster) CG32845 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)