RTF1 - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RTF1	ENSG00000137815	No diseases in record	No drugs in record	transcription factor activity, RNA polymerase II transcription factor binding single-stranded DNA binding protein binding RNA polymerase II C-terminal domain phosphoserine binding DNA binding RNA binding histone methyltransferase activity (H3-K4 specific) mating type region replication fork barrier binding	RTF1 (S. cerevisiae) rtfo-1 (C. elegans) Rtf1 (D. melanogaster) CG31702 (D. melanogaster) CG31703 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)