MEN1 - WRN

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MEN1	ENSG00000133895	parathyroid tumours pancreatic neuroendocrine tumour parathyroid adenoma pituitary adenoma pancreatic islet cell carcinoid	No drugs in record	four-way junction DNA binding Y-form DNA binding chromatin binding double-stranded DNA binding protein binding protein binding, bridging transcription regulatory region DNA binding protein N-terminus binding R-SMAD binding histone-lysine N-methyltransferase activity	Mnn1 (D. melanogaster)
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)