WRN - HCFC1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)
HCFC1	ENSG00000172534	No diseases in record	No drugs in record	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding identical protein binding cadherin binding involved in cell-cell adhesion histone acetyltransferase activity (H4-K5 specific) histone acetyltransferase activity (H4-K8 specific) histone acetyltransferase activity (H4-K16 specific)	KEL1 (S. cerevisiae) KEL2 (S. cerevisiae) hcf-1 (C. elegans)