WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000108984 MAP2K6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.775579 View
ENSG00000135476 ESPL1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.775284 View
ENSG00000115904 SOS1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.77492 View
ENSG00000118515 SGK1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.774908 View
ENSG00000080603 SRCAP ENSG00000165392 WRN H. sapiens SSL Slorth 0.774673 View
ENSG00000131711 MAP1B ENSG00000165392 WRN H. sapiens SSL Slorth 0.774609 View
ENSG00000111596 CNOT2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.774461 View
ENSG00000165392 WRN ENSG00000187109 NAP1L1 H. sapiens SSL Slorth 0.774289 View
ENSG00000165392 WRN ENSG00000167325 RRM1 H. sapiens SSL Slorth 0.77395 View
ENSG00000112249 ASCC3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.77382 View
ENSG00000165392 WRN ENSG00000170027 YWHAG H. sapiens SSL Slorth 0.773743 View
ENSG00000133706 LARS ENSG00000165392 WRN H. sapiens SSL Slorth 0.773672 View
ENSG00000128578 STRIP2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.7734 View
ENSG00000113643 RARS ENSG00000165392 WRN H. sapiens SSL Slorth 0.773162 View
ENSG00000134574 DDB2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.773135 View
ENSG00000109458 GAB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.773032 View
ENSG00000071127 WDR1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.772506 View
ENSG00000108312 UBTF ENSG00000165392 WRN H. sapiens SSL Slorth 0.771876 View
ENSG00000113658 SMAD5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.771657 View
ENSG00000131023 LATS1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.771185 View
ENSG00000160293 VAV2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.770503 View
ENSG00000083168 KAT6A ENSG00000165392 WRN H. sapiens SSL Slorth 0.770482 View
ENSG00000165392 WRN ENSG00000175203 DCTN2 H. sapiens SSL Slorth 0.770274 View
ENSG00000137055 PLAA ENSG00000165392 WRN H. sapiens SSL Slorth 0.769998 View
ENSG00000159459 UBR1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.76997 View
ENSG00000108468 CBX1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.769582 View
ENSG00000144381 HSPD1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.769301 View
ENSG00000143632 ACTA1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.769244 View
ENSG00000074181 NOTCH3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.769011 View
ENSG00000096746 HNRNPH3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.768961 View
ENSG00000101336 HCK ENSG00000165392 WRN H. sapiens SSL Slorth 0.768844 View
ENSG00000132388 UBE2G1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.76867 View
ENSG00000163743 RCHY1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.768505 View
ENSG00000165392 WRN ENSG00000166333 ILK H. sapiens SSL Slorth 0.768477 View
ENSG00000108587 GOSR1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.768405 View
ENSG00000112335 SNX3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.768369 View
ENSG00000138081 FBXO11 ENSG00000165392 WRN H. sapiens SSL Slorth 0.768275 View
ENSG00000134899 ERCC5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.768071 View
ENSG00000112282 MED23 ENSG00000165392 WRN H. sapiens SSL Slorth 0.767831 View
ENSG00000160201 U2AF1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.767779 View