Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
SGK1
|
ENSG00000118515
|
Nodular lymphocyte predominant Hodgkin lymphoma
|
No drugs in record
|
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
calcium channel regulator activity
protein binding
ATP binding
potassium channel regulator activity
sodium channel regulator activity
chloride channel regulator activity
|
SCH9 (S. cerevisiae)
YPK1 (S. cerevisiae)
YPK2 (S. cerevisiae)
sgk-1 (C. elegans)
|
WRN
|
ENSG00000165392
|
osteosarcoma
meningioma
other tumour types
|
No drugs in record
|
magnesium ion binding
Y-form DNA binding
bubble DNA binding
DNA binding
DNA helicase activity
chromatin binding
ATP-dependent DNA helicase activity
helicase activity
exonuclease activity
protein binding
ATP binding
3'-5' exonuclease activity
four-way junction helicase activity
ATPase activity
manganese ion binding
protein complex binding
protein homodimerization activity
3'-5' DNA helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
|
SGS1 (S. cerevisiae)
wrn-1 (C. elegans)
|