WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000161547 SRSF2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.80872 View
ENSG00000034713 GABARAPL2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.808381 View
ENSG00000115866 DARS ENSG00000165392 WRN H. sapiens SSL Slorth 0.807844 View
ENSG00000088833 NSFL1C ENSG00000165392 WRN H. sapiens SSL Slorth 0.806748 View
ENSG00000165392 WRN ENSG00000167005 NUDT21 H. sapiens SSL Slorth 0.805981 View
ENSG00000105329 TGFB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.804889 View
ENSG00000140455 USP3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.803999 View
ENSG00000121892 PDS5A ENSG00000165392 WRN H. sapiens SSL Slorth 0.803744 View
ENSG00000090376 IRAK3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.803711 View
ENSG00000138107 ACTR1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.803584 View
ENSG00000077782 FGFR1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.802243 View
ENSG00000157456 CCNB2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.801567 View
ENSG00000136152 COG3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.801274 View
ENSG00000083642 PDS5B ENSG00000165392 WRN H. sapiens SSL Slorth 0.801102 View
ENSG00000113460 BRIX1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.800952 View
ENSG00000109819 PPARGC1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.800926 View
ENSG00000105401 CDC37 ENSG00000165392 WRN H. sapiens SSL Slorth 0.800867 View
ENSG00000165392 WRN ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.800811 View
ENSG00000119912 IDE ENSG00000165392 WRN H. sapiens SSL Slorth 0.800574 View
ENSG00000077254 USP33 ENSG00000165392 WRN H. sapiens SSL Slorth 0.80024 View
ENSG00000099783 HNRNPM ENSG00000165392 WRN H. sapiens SSL Slorth 0.799524 View
ENSG00000134014 ELP3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.799286 View
ENSG00000165392 WRN ENSG00000173327 MAP3K11 H. sapiens SSL Slorth 0.798489 View
ENSG00000163161 ERCC3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.798381 View
ENSG00000155438 NIFK ENSG00000165392 WRN H. sapiens SSL Slorth 0.798208 View
ENSG00000004975 DVL2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.79774 View
ENSG00000070770 CSNK2A2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.797678 View
ENSG00000140682 TGFB1I1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.797633 View
ENSG00000066027 PPP2R5A ENSG00000165392 WRN H. sapiens SSL Slorth 0.797286 View
ENSG00000118058 KMT2A ENSG00000165392 WRN H. sapiens SSL Slorth 0.797249 View
ENSG00000077080 ACTL6B ENSG00000165392 WRN H. sapiens SSL Slorth 0.797123 View
ENSG00000136986 DERL1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.796989 View
ENSG00000081189 MEF2C ENSG00000165392 WRN H. sapiens SSL Slorth 0.79694 View
ENSG00000142230 SAE1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.796546 View
ENSG00000111424 VDR ENSG00000165392 WRN H. sapiens SSL Slorth 0.796318 View
ENSG00000141030 COPS3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.796247 View
ENSG00000131462 TUBG1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.795035 View
ENSG00000124193 SRSF6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.794681 View
ENSG00000165392 WRN ENSG00000181788 SIAH2 H. sapiens SSL Slorth 0.794593 View
ENSG00000014138 POLA2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.794589 View