WRN - PARK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
WRN	ENSG00000165392	osteosarcoma meningioma other tumour types	No drugs in record	magnesium ion binding Y-form DNA binding bubble DNA binding DNA binding DNA helicase activity chromatin binding ATP-dependent DNA helicase activity helicase activity exonuclease activity protein binding ATP binding 3'-5' exonuclease activity four-way junction helicase activity ATPase activity manganese ion binding protein complex binding protein homodimerization activity 3'-5' DNA helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding	SGS1 (S. cerevisiae) wrn-1 (C. elegans)
PARK2	ENSG00000185345	No diseases in record	No drugs in record	transcription regulatory region sequence-specific DNA binding G-protein coupled receptor binding transcription factor activity, sequence-specific DNA binding actin binding ubiquitin-protein transferase activity protein binding beta-catenin binding zinc ion binding tubulin binding SH3 domain binding enzyme binding kinase binding protein kinase binding PDZ domain binding Hsp70 protein binding heat shock protein binding ubiquitin conjugating enzyme binding ubiquitin protein ligase binding identical protein binding histone deacetylase binding ubiquitin binding phospholipase binding chaperone binding ubiquitin protein ligase activity cullin family protein binding ubiquitin protein ligase activity involved in ERAD pathway ubiquitin-specific protease binding F-box domain binding	No GO terms in record