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Slorth
PDGFRB - WRN
H. sapiens
SSL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
PDGFRB
ENSG00000113721
MPN
AML
CMML
CML
BECAPLERMIN
DASATINIB
IMATINIB
NINTEDANIB
PAZOPANIB
REGORAFENIB
SORAFENIB
SUNITINIB
protein tyrosine kinase activity
platelet activating factor receptor activity
platelet-derived growth factor-activated receptor activity
platelet-derived growth factor beta-receptor activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
platelet-derived growth factor receptor binding
protein binding
ATP binding
enzyme binding
protein kinase binding
vascular endothelial growth factor binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
platelet-derived growth factor binding
Pvr (D. melanogaster)
WRN
ENSG00000165392
osteosarcoma
meningioma
other tumour types
No drugs in record
magnesium ion binding
Y-form DNA binding
bubble DNA binding
DNA binding
DNA helicase activity
chromatin binding
ATP-dependent DNA helicase activity
helicase activity
exonuclease activity
protein binding
ATP binding
3'-5' exonuclease activity
four-way junction helicase activity
ATPase activity
manganese ion binding
protein complex binding
protein homodimerization activity
3'-5' DNA helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
SGS1 (S. cerevisiae)
wrn-1 (C. elegans)