PTPN11

ENSG00000179295 - H. sapiens

Pathways

Go term Description
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005070 SH3/SH2 adaptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0019904 protein domain specific binding
GO:0030971 receptor tyrosine kinase binding
GO:0031748 D1 dopamine receptor binding
GO:0043274 phospholipase binding
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0050839 cell adhesion molecule binding
GO:0051428 peptide hormone receptor binding

Drugs

No drugs in record

Diseases

Disease Name
JMML
AML
MDS

Orthologs

Gene Organism
PTP1 S. cerevisiae
ptp-2 C. elegans
csw D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000179295 PTPN11 ENSG00000214517 PPME1 H. sapiens SDL Slorth 0.94965 View
ENSG00000146094 DOK3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.949347 View
ENSG00000179295 PTPN11 ENSG00000254087 LYN H. sapiens SDL Slorth 0.9491 View
ENSG00000133703 KRAS ENSG00000179295 PTPN11 H. sapiens SSL Slorth 0.94884 View
ENSG00000179295 PTPN11 ENSG00000196396 PTPN1 H. sapiens SDL Slorth 0.948447 View
ENSG00000078018 MAP2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.948187 View
ENSG00000151422 FER ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.947796 View
ENSG00000179295 PTPN11 ENSG00000198873 GRK5 H. sapiens SDL Slorth 0.947241 View
ENSG00000065613 SLK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.946971 View
ENSG00000146648 EGFR ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.946206 View
ENSG00000134853 PDGFRA ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.945889 View
ENSG00000106803 SEC61B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.945812 View
ENSG00000037280 FLT4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.945641 View
ENSG00000162434 JAK1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.9452 View
ENSG00000132155 RAF1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.944859 View
ENSG00000105647 PIK3R2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.944441 View
ENSG00000115325 DOK1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.942865 View
ENSG00000100311 PDGFB ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.94286 View
ENSG00000109670 FBXW7 ENSG00000179295 PTPN11 H. sapiens SSL Slorth 0.942813 View
ENSG00000101350 KIF3B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.941828 View
ENSG00000131437 KIF3A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.941828 View
ENSG00000114737 CISH ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.941738 View
ENSG00000169230 PRELID1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.941267 View
ENSG00000168610 STAT3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.94125 View
ENSG00000140538 NTRK3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.940614 View
ENSG00000141510 TP53 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.939029 View
ENSG00000160271 RALGDS ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.938804 View
ENSG00000171094 ALK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.938784 View
ENSG00000179295 PTPN11 ENSG00000182208 MOB2 H. sapiens SDL Slorth 0.938364 View
ENSG00000100485 SOS2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.938038 View
ENSG00000179295 PTPN11 ENSG00000198648 STK39 H. sapiens SDL Slorth 0.937305 View
ENSG00000096968 JAK2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.937105 View
ENSG00000134215 VAV3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.93608 View
ENSG00000179295 PTPN11 ENSG00000179776 CDH5 H. sapiens SDL Slorth 0.935904 View
ENSG00000179295 PTPN11 ENSG00000180353 HCLS1 H. sapiens SDL Slorth 0.93527 View
ENSG00000168036 CTNNB1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.9351 View
ENSG00000179295 PTPN11 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.934235 View
ENSG00000164056 SPRY1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.934096 View
ENSG00000168724 DNAJC21 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.933631 View
ENSG00000157601 MX1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.933094 View