PTPN11

ENSG00000179295 - H. sapiens

Pathways

Go term Description
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005070 SH3/SH2 adaptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0019904 protein domain specific binding
GO:0030971 receptor tyrosine kinase binding
GO:0031748 D1 dopamine receptor binding
GO:0043274 phospholipase binding
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0050839 cell adhesion molecule binding
GO:0051428 peptide hormone receptor binding

Drugs

No drugs in record

Diseases

Disease Name
JMML
AML
MDS

Orthologs

Gene Organism
PTP1 S. cerevisiae
ptp-2 C. elegans
csw D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000008196 TFAP2B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.969643 View
ENSG00000116990 MYCL ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.969403 View
ENSG00000157216 SSBP3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.969312 View
ENSG00000176170 SPHK1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.969107 View
ENSG00000115592 PRKAG3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.968993 View
ENSG00000064489 BORCS8-MEF2B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.968993 View
ENSG00000179295 PTPN11 ENSG00000185338 SOCS1 H. sapiens SDL Slorth 0.96889 View
ENSG00000179295 PTPN11 ENSG00000180176 TH H. sapiens SDL Slorth 0.968865 View
ENSG00000179295 PTPN11 ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.968575 View
ENSG00000107263 RAPGEF1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.968508 View
ENSG00000112246 SIM1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.968495 View
ENSG00000063438 AHRR ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.968495 View
ENSG00000151322 NPAS3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.968495 View
ENSG00000130751 NPAS1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.968495 View
ENSG00000164919 COX6C ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.968223 View
ENSG00000179295 PTPN11 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.967627 View
ENSG00000164284 GRPEL2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.967608 View
ENSG00000122592 HOXA7 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.967292 View
ENSG00000106689 LHX2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.967292 View
ENSG00000165125 TRPV6 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.96716 View
ENSG00000011454 RABGAP1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.967149 View
ENSG00000179295 PTPN11 ENSG00000205726 ITSN1 H. sapiens SDL Slorth 0.966949 View
ENSG00000179295 PTPN11 ENSG00000187522 HSPA14 H. sapiens SDL Slorth 0.966391 View
ENSG00000179295 PTPN11 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.966391 View
ENSG00000168542 COL3A1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.966383 View
ENSG00000179295 PTPN11 ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.965638 View
ENSG00000146701 MDH2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.965518 View
ENSG00000137845 ADAM10 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.964982 View
ENSG00000123612 ACVR1C ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.964715 View
ENSG00000151150 ANK3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.964594 View
ENSG00000179295 PTPN11 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.964322 View
ENSG00000076344 RGS11 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.964269 View
ENSG00000179295 PTPN11 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.963924 View
ENSG00000179295 PTPN11 ENSG00000182621 PLCB1 H. sapiens SDL Slorth 0.963604 View
ENSG00000102145 GATA1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.962981 View
ENSG00000117707 PROX1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.962942 View
ENSG00000100393 EP300 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.962935 View
ENSG00000179295 PTPN11 ENSG00000254505 CHMP4A H. sapiens SDL Slorth 0.962757 View
ENSG00000163394 CCKAR ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.962553 View
ENSG00000179295 PTPN11 ENSG00000184557 SOCS3 H. sapiens SDL Slorth 0.962326 View