PTPN11

ENSG00000179295 - H. sapiens

Pathways

Go term Description
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005070 SH3/SH2 adaptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0019904 protein domain specific binding
GO:0030971 receptor tyrosine kinase binding
GO:0031748 D1 dopamine receptor binding
GO:0043274 phospholipase binding
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0050839 cell adhesion molecule binding
GO:0051428 peptide hormone receptor binding

Drugs

No drugs in record

Diseases

Disease Name
JMML
AML
MDS

Orthologs

Gene Organism
PTP1 S. cerevisiae
ptp-2 C. elegans
csw D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000168418 KCNG4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976498 View
ENSG00000041982 TNC ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976436 View
ENSG00000160360 GPSM1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976426 View
ENSG00000078114 NEBL ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976403 View
ENSG00000125656 CLPP ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976386 View
ENSG00000048462 TNFRSF17 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976377 View
ENSG00000171016 PYGO1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976321 View
ENSG00000070404 FSTL3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976262 View
ENSG00000150991 UBC ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976184 View
ENSG00000072315 TRPC5 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976085 View
ENSG00000058404 CAMK2B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.976085 View
ENSG00000105204 DYRK1B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975929 View
ENSG00000102781 KATNAL1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975691 View
ENSG00000140750 ARHGAP17 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975482 View
ENSG00000139998 RAB15 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975423 View
ENSG00000135312 HTR1B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975414 View
ENSG00000165819 METTL3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975397 View
ENSG00000061918 GUCY1B3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975389 View
ENSG00000048540 LMO3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975354 View
ENSG00000114861 FOXP1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975354 View
ENSG00000143355 LHX9 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975354 View
ENSG00000137166 FOXP4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975354 View
ENSG00000115216 NRBP1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97532 View
ENSG00000115507 OTX1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97532 View
ENSG00000070476 ZXDC ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975132 View
ENSG00000164741 DLC1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975049 View
ENSG00000160193 WDR4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.975009 View
ENSG00000140199 SLC12A6 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.974737 View
ENSG00000090889 KIF4A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97463 View
ENSG00000075340 ADD2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.974576 View
ENSG00000095397 WHRN ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97428 View
ENSG00000085185 BCORL1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.974144 View
ENSG00000171189 GRIK1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.974098 View
ENSG00000153132 CLGN ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.974098 View
ENSG00000115616 SLC9A2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.974098 View
ENSG00000166228 PCBD1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97408 View
ENSG00000174567 GOLT1A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.973936 View
ENSG00000127329 PTPRB ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97392 View
ENSG00000114554 PLXNA1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.973904 View
ENSG00000179295 PTPN11 ENSG00000188130 MAPK12 H. sapiens SDL Slorth 0.973696 View