PTPN11

ENSG00000179295 - H. sapiens

Pathways

Go term Description
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005070 SH3/SH2 adaptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0019904 protein domain specific binding
GO:0030971 receptor tyrosine kinase binding
GO:0031748 D1 dopamine receptor binding
GO:0043274 phospholipase binding
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0050839 cell adhesion molecule binding
GO:0051428 peptide hormone receptor binding

Drugs

No drugs in record

Diseases

Disease Name
JMML
AML
MDS

Orthologs

Gene Organism
PTP1 S. cerevisiae
ptp-2 C. elegans
csw D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000179295 PTPN11 ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.962004 View
ENSG00000111859 NEDD9 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.961654 View
ENSG00000179295 PTPN11 ENSG00000185950 IRS2 H. sapiens SDL Slorth 0.961087 View
ENSG00000107282 APBA1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.960492 View
ENSG00000108773 KAT2A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.960078 View
ENSG00000105287 PRKD2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.959883 View
ENSG00000162385 MAGOH ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.959837 View
ENSG00000179295 PTPN11 ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.959804 View
ENSG00000133124 IRS4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.95946 View
ENSG00000177885 GRB2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.959409 View
ENSG00000108947 EFNB3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.959137 View
ENSG00000178726 THBD ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.95863 View
ENSG00000149781 FERMT3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.958478 View
ENSG00000179295 PTPN11 ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.958315 View
ENSG00000112319 EYA4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.957479 View
ENSG00000080224 EPHA6 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.956599 View
ENSG00000179295 PTPN11 ENSG00000185122 HSF1 H. sapiens SDL Slorth 0.955997 View
ENSG00000007264 MATK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.95563 View
ENSG00000163064 EN1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.95536 View
ENSG00000160293 VAV2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.955356 View
ENSG00000113263 ITK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.955317 View
ENSG00000103653 CSK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.955149 View
ENSG00000104129 DNAJC17 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.955002 View
ENSG00000005882 PDK2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.954957 View
ENSG00000179295 PTPN11 ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.954748 View
ENSG00000072736 NFATC3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.954427 View
ENSG00000171150 SOCS5 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.954392 View
ENSG00000169282 KCNAB1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.95383 View
ENSG00000117461 PIK3R3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.953705 View
ENSG00000173757 STAT5B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.953695 View
ENSG00000136573 BLK ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.953667 View
ENSG00000115290 GRB14 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.953472 View
ENSG00000070778 PTPN21 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.953322 View
ENSG00000110395 CBL ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.952829 View
ENSG00000178562 CD28 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.952825 View
ENSG00000033327 GAB2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.952546 View
ENSG00000178188 SH2B1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.952437 View
ENSG00000071242 RPS6KA2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.952065 View
ENSG00000010810 FYN ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.951073 View
ENSG00000144034 TPRKB ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.950469 View