PTPN11

ENSG00000179295 - H. sapiens

Pathways

Go term Description
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005070 SH3/SH2 adaptor activity
GO:0005158 insulin receptor binding
GO:0005515 protein binding
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0019904 protein domain specific binding
GO:0030971 receptor tyrosine kinase binding
GO:0031748 D1 dopamine receptor binding
GO:0043274 phospholipase binding
GO:0043560 insulin receptor substrate binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0050839 cell adhesion molecule binding
GO:0051428 peptide hormone receptor binding

Drugs

No drugs in record

Diseases

Disease Name
JMML
AML
MDS

Orthologs

Gene Organism
PTP1 S. cerevisiae
ptp-2 C. elegans
csw D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000169435 RASSF6 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.973656 View
ENSG00000146232 NFKBIE ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97361 View
ENSG00000166963 MAP1A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97332 View
ENSG00000167550 RHEBL1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.973272 View
ENSG00000016082 ISL1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.973108 View
ENSG00000170162 VGLL2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.973071 View
ENSG00000179295 PTPN11 ENSG00000184937 WT1 H. sapiens SDL Slorth 0.973058 View
ENSG00000179295 PTPN11 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.97294 View
ENSG00000134438 RAX ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97288 View
ENSG00000118900 UBN1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.972871 View
ENSG00000079432 CIC ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.972681 View
ENSG00000156345 CDK20 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.972372 View
ENSG00000165832 TRUB1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.972105 View
ENSG00000163536 SERPINI1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971846 View
ENSG00000145331 TRMT10A ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971821 View
ENSG00000143252 SDHC ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971821 View
ENSG00000148840 PPRC1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971782 View
ENSG00000143257 NR1I3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971621 View
ENSG00000151746 BICD1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971605 View
ENSG00000126785 RHOJ ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971491 View
ENSG00000179295 PTPN11 ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.971446 View
ENSG00000100228 RAB36 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971433 View
ENSG00000138594 TMOD3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971383 View
ENSG00000136944 LMX1B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971376 View
ENSG00000179295 PTPN11 ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.971258 View
ENSG00000152578 GRIA4 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97106 View
ENSG00000135776 ABCB10 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97103 View
ENSG00000159263 SIM2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.971002 View
ENSG00000114315 HES1 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97083 View
ENSG00000125967 NECAB3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.97083 View
ENSG00000171450 CDK5R2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.970753 View
ENSG00000105737 GRIK5 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.970619 View
ENSG00000124232 RBPJL ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.970512 View
ENSG00000099365 STX1B ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.970452 View
ENSG00000082146 STRADB ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.970436 View
ENSG00000162512 SDC3 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.970007 View
ENSG00000111049 MYF5 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.969949 View
ENSG00000119729 RHOQ ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.969789 View
ENSG00000179295 PTPN11 ENSG00000197943 PLCG2 H. sapiens SDL Slorth 0.969659 View
ENSG00000165238 WNK2 ENSG00000179295 PTPN11 H. sapiens SDL Slorth 0.969648 View