PTPN11 - PTPN1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PTPN11	ENSG00000179295	JMML AML MDS	No drugs in record	phosphoprotein phosphatase activity protein tyrosine phosphatase activity non-membrane spanning protein tyrosine phosphatase activity SH3/SH2 adaptor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein domain specific binding receptor tyrosine kinase binding D1 dopamine receptor binding phospholipase binding insulin receptor substrate binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity cell adhesion molecule binding peptide hormone receptor binding	PTP1 (S. cerevisiae) ptp-2 (C. elegans) csw (D. melanogaster)
PTPN1	ENSG00000196396	No diseases in record	No drugs in record	protein tyrosine phosphatase activity insulin receptor binding protein binding zinc ion binding enzyme binding protein kinase binding receptor tyrosine kinase binding ephrin receptor binding protein phosphatase 2A binding cadherin binding involved in cell-cell adhesion	Ptp61F (D. melanogaster)