TOP2B

ENSG00000077097 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008301 DNA binding, bending
GO:0019899 enzyme binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
ETOPOSIDE DNA topoisomerase II inhibitor
TENIPOSIDE DNA topoisomerase II inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2 S. cerevisiae
cin-4 C. elegans
top-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077097 TOP2B ENSG00000170312 CDK1 H. sapiens SSL Slorth 0.829524 View
ENSG00000077097 TOP2B ENSG00000144381 HSPD1 H. sapiens SSL Slorth 0.829489 View
ENSG00000077097 TOP2B ENSG00000108953 YWHAE H. sapiens SSL Slorth 0.829452 View
ENSG00000077097 TOP2B ENSG00000170027 YWHAG H. sapiens SSL Slorth 0.829339 View
ENSG00000077097 TOP2B ENSG00000078043 PIAS2 H. sapiens SSL Slorth 0.829274 View
ENSG00000077097 TOP2B ENSG00000127445 PIN1 H. sapiens SSL Slorth 0.82903 View
ENSG00000077097 TOP2B ENSG00000215301 DDX3X H. sapiens SSL Slorth 0.827841 View
ENSG00000077097 TOP2B ENSG00000167005 NUDT21 H. sapiens SSL Slorth 0.826913 View
ENSG00000077097 TOP2B ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.826684 View
ENSG00000077097 TOP2B ENSG00000145604 SKP2 H. sapiens SSL Slorth 0.826589 View
ENSG00000077097 TOP2B ENSG00000177189 RPS6KA3 H. sapiens SSL Slorth 0.826498 View
ENSG00000077097 TOP2B ENSG00000169375 SIN3A H. sapiens SSL Slorth 0.826419 View
ENSG00000077097 TOP2B ENSG00000112062 MAPK14 H. sapiens SSL Slorth 0.825633 View
ENSG00000065427 KARS ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.825544 View
ENSG00000077097 TOP2B ENSG00000136997 MYC H. sapiens SSL Slorth 0.82537 View
ENSG00000077097 TOP2B ENSG00000178999 AURKB H. sapiens SSL Slorth 0.825253 View
ENSG00000077097 TOP2B ENSG00000134899 ERCC5 H. sapiens SSL Slorth 0.824791 View
ENSG00000077097 TOP2B ENSG00000107404 DVL1 H. sapiens SSL Slorth 0.824148 View
ENSG00000077097 TOP2B ENSG00000196628 TCF4 H. sapiens SSL Slorth 0.823736 View
ENSG00000075711 DLG1 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.823582 View
ENSG00000077097 TOP2B ENSG00000136450 SRSF1 H. sapiens SSL Slorth 0.823153 View
ENSG00000077097 TOP2B ENSG00000103194 USP10 H. sapiens SSL Slorth 0.822884 View
ENSG00000077097 TOP2B ENSG00000103275 UBE2I H. sapiens SSL Slorth 0.822859 View
ENSG00000077097 TOP2B ENSG00000169083 AR H. sapiens SSL Slorth 0.822806 View
ENSG00000077097 TOP2B ENSG00000109062 SLC9A3R1 H. sapiens SSL Slorth 0.822684 View
ENSG00000077097 TOP2B ENSG00000150753 CCT5 H. sapiens SSL Slorth 0.822614 View
ENSG00000077097 TOP2B ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.822528 View
ENSG00000053372 MRTO4 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.821722 View
ENSG00000077097 TOP2B ENSG00000104695 PPP2CB H. sapiens SSL Slorth 0.820187 View
ENSG00000077097 TOP2B ENSG00000114423 CBLB H. sapiens SSL Slorth 0.818907 View
ENSG00000077097 TOP2B ENSG00000109606 DHX15 H. sapiens SSL Slorth 0.818678 View
ENSG00000077097 TOP2B ENSG00000111424 VDR H. sapiens SSL Slorth 0.817823 View
ENSG00000077097 TOP2B ENSG00000158402 CDC25C H. sapiens SSL Slorth 0.817709 View
ENSG00000077097 TOP2B ENSG00000170606 HSPA4 H. sapiens SSL Slorth 0.817639 View
ENSG00000077097 TOP2B ENSG00000123374 CDK2 H. sapiens SSL Slorth 0.816318 View
ENSG00000077097 TOP2B ENSG00000141551 CSNK1D H. sapiens SSL Slorth 0.816281 View
ENSG00000077097 TOP2B ENSG00000166226 CCT2 H. sapiens SSL Slorth 0.816275 View
ENSG00000077097 TOP2B ENSG00000141968 VAV1 H. sapiens SSL Slorth 0.815774 View
ENSG00000077097 TOP2B ENSG00000145386 CCNA2 H. sapiens SSL Slorth 0.815562 View
ENSG00000077097 TOP2B ENSG00000116062 MSH6 H. sapiens SSL Slorth 0.81521 View