TOP2B - VAV1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
VAV1	ENSG00000141968	T-cell lymphoma	No drugs in record	transcription factor activity, sequence-specific DNA binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding Rac guanyl-nucleotide exchange factor activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	CDC24 (S. cerevisiae)