TOP2B

ENSG00000077097 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008301 DNA binding, bending
GO:0019899 enzyme binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
ETOPOSIDE DNA topoisomerase II inhibitor
TENIPOSIDE DNA topoisomerase II inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2 S. cerevisiae
cin-4 C. elegans
top-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077097 TOP2B ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.767769 View
ENSG00000077097 TOP2B ENSG00000160201 U2AF1 H. sapiens SSL Slorth 0.767716 View
ENSG00000077097 TOP2B ENSG00000187735 TCEA1 H. sapiens SSL Slorth 0.767638 View
ENSG00000077097 TOP2B ENSG00000123136 DDX39A H. sapiens SSL Slorth 0.767588 View
ENSG00000077097 TOP2B ENSG00000085832 EPS15 H. sapiens SSL Slorth 0.767575 View
ENSG00000077097 TOP2B ENSG00000170315 UBB H. sapiens SSL Slorth 0.767521 View
ENSG00000077097 TOP2B ENSG00000136279 DBNL H. sapiens SSL Slorth 0.766449 View
ENSG00000077097 TOP2B ENSG00000150459 SAP18 H. sapiens SSL Slorth 0.766282 View
ENSG00000077097 TOP2B ENSG00000151090 THRB H. sapiens SSL Slorth 0.76475 View
ENSG00000077097 TOP2B ENSG00000099995 SF3A1 H. sapiens SSL Slorth 0.764431 View
ENSG00000077097 TOP2B ENSG00000248333 CDK11B H. sapiens SSL Slorth 0.76411 View
ENSG00000077097 TOP2B ENSG00000133895 MEN1 H. sapiens SSL Slorth 0.763451 View
ENSG00000077097 TOP2B ENSG00000145555 MYO10 H. sapiens SSL Slorth 0.763315 View
ENSG00000077097 TOP2B ENSG00000168439 STIP1 H. sapiens SSL Slorth 0.763254 View
ENSG00000077097 TOP2B ENSG00000123908 AGO2 H. sapiens SSL Slorth 0.763084 View
ENSG00000077097 TOP2B ENSG00000165731 RET H. sapiens SSL Slorth 0.763063 View
ENSG00000077097 TOP2B ENSG00000163558 PRKCI H. sapiens SSL Slorth 0.762558 View
ENSG00000077097 TOP2B ENSG00000171960 PPIH H. sapiens SSL Slorth 0.762274 View
ENSG00000077097 TOP2B ENSG00000101224 CDC25B H. sapiens SSL Slorth 0.76162 View
ENSG00000077097 TOP2B ENSG00000107201 DDX58 H. sapiens SSL Slorth 0.761349 View
ENSG00000077097 TOP2B ENSG00000139842 CUL4A H. sapiens SSL Slorth 0.761149 View
ENSG00000077097 TOP2B ENSG00000100401 RANGAP1 H. sapiens SSL Slorth 0.760785 View
ENSG00000077097 TOP2B ENSG00000167325 RRM1 H. sapiens SSL Slorth 0.760743 View
ENSG00000077097 TOP2B ENSG00000182208 MOB2 H. sapiens SSL Slorth 0.760109 View
ENSG00000077097 TOP2B ENSG00000164045 CDC25A H. sapiens SSL Slorth 0.759951 View
ENSG00000077097 TOP2B ENSG00000157349 DDX19B H. sapiens SSL Slorth 0.75977 View
ENSG00000077097 TOP2B ENSG00000112079 STK38 H. sapiens SSL Slorth 0.759302 View
ENSG00000077097 TOP2B ENSG00000108654 DDX5 H. sapiens SSL Slorth 0.759132 View
ENSG00000077097 TOP2B ENSG00000153201 RANBP2 H. sapiens SSL Slorth 0.759014 View
ENSG00000077097 TOP2B ENSG00000113643 RARS H. sapiens SSL Slorth 0.7585 View
ENSG00000077097 TOP2B ENSG00000110107 PRPF19 H. sapiens SSL Slorth 0.757825 View
ENSG00000077097 TOP2B ENSG00000106105 GARS H. sapiens SSL Slorth 0.757585 View
ENSG00000077097 TOP2B ENSG00000172845 SP3 H. sapiens SSL Slorth 0.757297 View
ENSG00000077097 TOP2B ENSG00000173757 STAT5B H. sapiens SSL Slorth 0.75719 View
ENSG00000077097 TOP2B ENSG00000166855 CLPX H. sapiens SSL Slorth 0.756061 View
ENSG00000077097 TOP2B ENSG00000100650 SRSF5 H. sapiens SSL Slorth 0.755776 View
ENSG00000077097 TOP2B ENSG00000119912 IDE H. sapiens SSL Slorth 0.75555 View
ENSG00000077097 TOP2B ENSG00000123124 WWP1 H. sapiens SSL Slorth 0.755126 View
ENSG00000077097 TOP2B ENSG00000122566 HNRNPA2B1 H. sapiens SSL Slorth 0.755107 View
ENSG00000077097 TOP2B ENSG00000196305 IARS H. sapiens SSL Slorth 0.754854 View