TOP2B

ENSG00000077097 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008301 DNA binding, bending
GO:0019899 enzyme binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
ETOPOSIDE DNA topoisomerase II inhibitor
TENIPOSIDE DNA topoisomerase II inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2 S. cerevisiae
cin-4 C. elegans
top-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077097 TOP2B ENSG00000099817 POLR2E H. sapiens SSL Slorth 0.754412 View
ENSG00000077097 TOP2B ENSG00000133706 LARS H. sapiens SSL Slorth 0.75437 View
ENSG00000077097 TOP2B ENSG00000139154 AEBP2 H. sapiens SSL Slorth 0.753854 View
ENSG00000077097 TOP2B ENSG00000163029 SMC6 H. sapiens SSL Slorth 0.753473 View
ENSG00000077097 TOP2B ENSG00000175595 ERCC4 H. sapiens SSL Slorth 0.753295 View
ENSG00000077097 TOP2B ENSG00000141867 BRD4 H. sapiens SSL Slorth 0.752879 View
ENSG00000077097 TOP2B ENSG00000123358 NR4A1 H. sapiens SSL Slorth 0.752383 View
ENSG00000077097 TOP2B ENSG00000116016 EPAS1 H. sapiens SSL Slorth 0.752206 View
ENSG00000077097 TOP2B ENSG00000276618 RAD17 H. sapiens SSL Slorth 0.752054 View
ENSG00000077097 TOP2B ENSG00000198648 STK39 H. sapiens SSL Slorth 0.751906 View
ENSG00000077097 TOP2B ENSG00000198400 NTRK1 H. sapiens SSL Slorth 0.751213 View
ENSG00000077097 TOP2B ENSG00000114030 KPNA1 H. sapiens SSL Slorth 0.750825 View
ENSG00000077097 TOP2B ENSG00000169139 UBE2V2 H. sapiens SSL Slorth 0.750819 View
ENSG00000077097 TOP2B ENSG00000184216 IRAK1 H. sapiens SSL Slorth 0.750716 View