Go term | Description |
---|---|
GO:0003682 | chromatin binding |
GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity |
GO:0005080 | protein kinase C binding |
GO:0005524 | ATP binding |
GO:0008022 | protein C-terminus binding |
GO:0008301 | DNA binding, bending |
GO:0019899 | enzyme binding |
GO:0042826 | histone deacetylase binding |
GO:0046872 | metal ion binding |
GO:0046982 | protein heterodimerization activity |
Drug name | Description |
---|---|
ETOPOSIDE | DNA topoisomerase II inhibitor |
TENIPOSIDE | DNA topoisomerase II inhibitor |
No diseases in record
Gene | Organism | |
---|---|---|
TOP2 | S. cerevisiae | |
cin-4 | C. elegans | |
top-2 | C. elegans |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000012048 | BRCA1 | ENSG00000077097 | TOP2B | H. sapiens | SDL | Slorth | 0.987976 | View |
ENSG00000077097 | TOP2B | ENSG00000198900 | TOP1 | H. sapiens | SDL | Slorth | 0.987169 | View |
ENSG00000005339 | CREBBP | ENSG00000077097 | TOP2B | H. sapiens | SDL | Slorth | 0.985052 | View |
ENSG00000077097 | TOP2B | ENSG00000165392 | WRN | H. sapiens | SDL | Slorth | 0.981794 | View |
ENSG00000077097 | TOP2B | ENSG00000184428 | TOP1MT | H. sapiens | SDL | Slorth | 0.977648 | View |
ENSG00000077097 | TOP2B | ENSG00000178999 | AURKB | H. sapiens | SDL | Slorth | 0.97755 | View |
ENSG00000077097 | TOP2B | ENSG00000087274 | ADD1 | H. sapiens | SDL | Slorth | 0.977436 | View |
ENSG00000077097 | TOP2B | ENSG00000111642 | CHD4 | H. sapiens | SDL | Slorth | 0.977423 | View |
ENSG00000077097 | TOP2B | ENSG00000150991 | UBC | H. sapiens | SDL | Slorth | 0.976748 | View |
ENSG00000077097 | TOP2B | ENSG00000083642 | PDS5B | H. sapiens | SDL | Slorth | 0.975955 | View |
ENSG00000077097 | TOP2B | ENSG00000132646 | PCNA | H. sapiens | SDL | Slorth | 0.975023 | View |
ENSG00000077097 | TOP2B | ENSG00000175197 | DDIT3 | H. sapiens | SDL | Slorth | 0.973805 | View |
ENSG00000010810 | FYN | ENSG00000077097 | TOP2B | H. sapiens | SSL | Slorth | 0.972995 | View |
ENSG00000077097 | TOP2B | ENSG00000093009 | CDC45 | H. sapiens | SDL | Slorth | 0.972869 | View |
ENSG00000077097 | TOP2B | ENSG00000153147 | SMARCA5 | H. sapiens | SDL | Slorth | 0.972589 | View |
ENSG00000077097 | TOP2B | ENSG00000196470 | SIAH1 | H. sapiens | SDL | Slorth | 0.972351 | View |
ENSG00000077097 | TOP2B | ENSG00000103126 | AXIN1 | H. sapiens | SDL | Slorth | 0.972274 | View |
ENSG00000077097 | TOP2B | ENSG00000099804 | CDC34 | H. sapiens | SDL | Slorth | 0.972272 | View |
ENSG00000077097 | TOP2B | ENSG00000138756 | BMP2K | H. sapiens | SDL | Slorth | 0.971651 | View |
ENSG00000077097 | TOP2B | ENSG00000184900 | SUMO3 | H. sapiens | SDL | Slorth | 0.970857 | View |
ENSG00000012048 | BRCA1 | ENSG00000077097 | TOP2B | H. sapiens | SSL | Slorth | 0.970511 | View |
ENSG00000077097 | TOP2B | ENSG00000127511 | SIN3B | H. sapiens | SDL | Slorth | 0.970076 | View |
ENSG00000077097 | TOP2B | ENSG00000114062 | UBE3A | H. sapiens | SDL | Slorth | 0.969627 | View |
ENSG00000005339 | CREBBP | ENSG00000077097 | TOP2B | H. sapiens | SSL | Slorth | 0.969525 | View |
ENSG00000077097 | TOP2B | ENSG00000141510 | TP53 | H. sapiens | SDL | Slorth | 0.969178 | View |
ENSG00000077097 | TOP2B | ENSG00000141480 | ARRB2 | H. sapiens | SDL | Slorth | 0.969132 | View |
ENSG00000077097 | TOP2B | ENSG00000137843 | PAK6 | H. sapiens | SDL | Slorth | 0.968692 | View |
ENSG00000077097 | TOP2B | ENSG00000149930 | TAOK2 | H. sapiens | SDL | Slorth | 0.968201 | View |
ENSG00000072401 | UBE2D1 | ENSG00000077097 | TOP2B | H. sapiens | SSL | Slorth | 0.967894 | View |
ENSG00000077097 | TOP2B | ENSG00000177606 | JUN | H. sapiens | SDL | Slorth | 0.967617 | View |
ENSG00000077097 | TOP2B | ENSG00000185379 | RAD51D | H. sapiens | SDL | Slorth | 0.967189 | View |
ENSG00000077097 | TOP2B | ENSG00000131747 | TOP2A | H. sapiens | SDL | Slorth | 0.967175 | View |
ENSG00000077097 | TOP2B | ENSG00000169047 | IRS1 | H. sapiens | SDL | Slorth | 0.967159 | View |
ENSG00000077097 | TOP2B | ENSG00000135476 | ESPL1 | H. sapiens | SDL | Slorth | 0.967113 | View |
ENSG00000077097 | TOP2B | ENSG00000130726 | TRIM28 | H. sapiens | SDL | Slorth | 0.966785 | View |
ENSG00000077097 | TOP2B | ENSG00000099956 | SMARCB1 | H. sapiens | SDL | Slorth | 0.96664 | View |
ENSG00000077097 | TOP2B | ENSG00000170345 | FOS | H. sapiens | SDL | Slorth | 0.966618 | View |
ENSG00000077097 | TOP2B | ENSG00000119866 | BCL11A | H. sapiens | SDL | Slorth | 0.966504 | View |
ENSG00000077097 | TOP2B | ENSG00000124813 | RUNX2 | H. sapiens | SDL | Slorth | 0.966183 | View |
ENSG00000077097 | TOP2B | ENSG00000164362 | TERT | H. sapiens | SDL | Slorth | 0.966058 | View |