TOP2B - CDC45

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
TOP2B ENSG00000077097

No diseases in record

ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
CDC45 ENSG00000093009

No diseases in record

No drugs in record

chromatin binding
DNA replication origin binding
single-stranded DNA binding
protein binding
3'-5' DNA helicase activity
CDC45 (S. cerevisiae)
CDC45L (D. melanogaster)