TOP2B - CHD4

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
TOP2B ENSG00000077097

No diseases in record

ETOPOSIDE
TENIPOSIDE
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
ATP binding
protein C-terminus binding
DNA binding, bending
enzyme binding
histone deacetylase binding
metal ion binding
protein heterodimerization activity
TOP2 (S. cerevisiae)
cin-4 (C. elegans)
top-2 (C. elegans)
CHD4 ENSG00000111642 uterine serous carcinoma

No drugs in record

RNA polymerase II repressing transcription factor binding
DNA binding
ATP-dependent DNA helicase activity
histone deacetylase activity
protein binding
ATP binding
microtubule binding
zinc ion binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
nucleosomal DNA binding
CHD1 (S. cerevisiae)
let-418 (C. elegans)
chd-3 (C. elegans)