TOP2B

ENSG00000077097 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008301 DNA binding, bending
GO:0019899 enzyme binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
ETOPOSIDE DNA topoisomerase II inhibitor
TENIPOSIDE DNA topoisomerase II inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2 S. cerevisiae
cin-4 C. elegans
top-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077097 TOP2B ENSG00000082701 GSK3B H. sapiens SDL Slorth 0.965794 View
ENSG00000077097 TOP2B ENSG00000135090 TAOK3 H. sapiens SDL Slorth 0.965642 View
ENSG00000077097 TOP2B ENSG00000149554 CHEK1 H. sapiens SDL Slorth 0.965629 View
ENSG00000077097 TOP2B ENSG00000100201 DDX17 H. sapiens SDL Slorth 0.965613 View
ENSG00000077097 TOP2B ENSG00000101945 SUV39H1 H. sapiens SDL Slorth 0.965495 View
ENSG00000077097 TOP2B ENSG00000103275 UBE2I H. sapiens SDL Slorth 0.96479 View
ENSG00000077097 TOP2B ENSG00000125977 EIF2S2 H. sapiens SDL Slorth 0.964777 View
ENSG00000077097 TOP2B ENSG00000107929 LARP4B H. sapiens SDL Slorth 0.964724 View
ENSG00000077097 TOP2B ENSG00000181163 NPM1 H. sapiens SDL Slorth 0.964441 View
ENSG00000077097 TOP2B ENSG00000125630 POLR1B H. sapiens SDL Slorth 0.964259 View
ENSG00000073111 MCM2 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.963815 View
ENSG00000077097 TOP2B ENSG00000087586 AURKA H. sapiens SDL Slorth 0.963744 View
ENSG00000077097 TOP2B ENSG00000102034 ELF4 H. sapiens SDL Slorth 0.963738 View
ENSG00000077097 TOP2B ENSG00000112701 SENP6 H. sapiens SDL Slorth 0.963517 View
ENSG00000062822 POLD1 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.963495 View
ENSG00000077097 TOP2B ENSG00000126261 UBA2 H. sapiens SDL Slorth 0.963177 View
ENSG00000077097 TOP2B ENSG00000170004 CHD3 H. sapiens SDL Slorth 0.962903 View
ENSG00000077097 TOP2B ENSG00000105229 PIAS4 H. sapiens SDL Slorth 0.962687 View
ENSG00000077097 TOP2B ENSG00000112144 ICK H. sapiens SDL Slorth 0.962584 View
ENSG00000058729 RIOK2 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.962502 View
ENSG00000077097 TOP2B ENSG00000155090 KLF10 H. sapiens SDL Slorth 0.962463 View
ENSG00000004700 RECQL ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.962429 View
ENSG00000077097 TOP2B ENSG00000165671 NSD1 H. sapiens SDL Slorth 0.962386 View
ENSG00000077097 TOP2B ENSG00000110092 CCND1 H. sapiens SDL Slorth 0.962378 View
ENSG00000077097 TOP2B ENSG00000097046 CDC7 H. sapiens SDL Slorth 0.962377 View
ENSG00000077097 TOP2B ENSG00000143799 PARP1 H. sapiens SDL Slorth 0.961951 View
ENSG00000077097 TOP2B ENSG00000100393 EP300 H. sapiens SDL Slorth 0.96194 View
ENSG00000077097 TOP2B ENSG00000116017 ARID3A H. sapiens SDL Slorth 0.96165 View
ENSG00000077097 TOP2B ENSG00000135829 DHX9 H. sapiens SDL Slorth 0.96152 View
ENSG00000077097 TOP2B ENSG00000108424 KPNB1 H. sapiens SDL Slorth 0.961361 View
ENSG00000077097 TOP2B ENSG00000141448 GATA6 H. sapiens SDL Slorth 0.961221 View
ENSG00000077097 TOP2B ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.961208 View
ENSG00000077097 TOP2B ENSG00000164736 SOX17 H. sapiens SDL Slorth 0.960941 View
ENSG00000077097 TOP2B ENSG00000100906 NFKBIA H. sapiens SDL Slorth 0.960683 View
ENSG00000077097 TOP2B ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.960674 View
ENSG00000077097 TOP2B ENSG00000133026 MYH10 H. sapiens SDL Slorth 0.960663 View
ENSG00000077097 TOP2B ENSG00000106462 EZH2 H. sapiens SDL Slorth 0.960447 View
ENSG00000077097 TOP2B ENSG00000108469 RECQL5 H. sapiens SDL Slorth 0.960108 View
ENSG00000077097 TOP2B ENSG00000108055 SMC3 H. sapiens SDL Slorth 0.960044 View
ENSG00000077097 TOP2B ENSG00000116044 NFE2L2 H. sapiens SDL Slorth 0.959993 View