TOP2B - SUV39H1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
SUV39H1	ENSG00000101945	No diseases in record	No drugs in record	transcription regulatory region sequence-specific DNA binding chromatin binding protein binding zinc ion binding S-adenosylmethionine-dependent methyltransferase activity histone-lysine N-methyltransferase activity histone methyltransferase activity histone methyltransferase activity (H3-K9 specific) protein N-terminus binding	SET2 (S. cerevisiae) Su(var)3-9 (D. melanogaster)