TOP2B - CHD3

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
CHD3	ENSG00000170004	No diseases in record	No drugs in record	DNA binding ATP-dependent DNA helicase activity helicase activity histone deacetylase activity protein binding ATP binding zinc ion binding ATP-dependent helicase activity nucleosome-dependent ATPase activity nucleosome binding	CHD1 (S. cerevisiae) Mi-2 (D. melanogaster) Chd3 (D. melanogaster)