TOP2B

ENSG00000077097 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008301 DNA binding, bending
GO:0019899 enzyme binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
ETOPOSIDE DNA topoisomerase II inhibitor
TENIPOSIDE DNA topoisomerase II inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2 S. cerevisiae
cin-4 C. elegans
top-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000063244 U2AF2 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.949458 View
ENSG00000077097 TOP2B ENSG00000149136 SSRP1 H. sapiens SDL Slorth 0.94941 View
ENSG00000077097 TOP2B ENSG00000155846 PPARGC1B H. sapiens SDL Slorth 0.949284 View
ENSG00000077097 TOP2B ENSG00000094804 CDC6 H. sapiens SDL Slorth 0.94928 View
ENSG00000077097 TOP2B ENSG00000089685 BIRC5 H. sapiens SDL Slorth 0.949209 View
ENSG00000077097 TOP2B ENSG00000152284 TCF7L1 H. sapiens SDL Slorth 0.94917 View
ENSG00000077097 TOP2B ENSG00000081059 TCF7 H. sapiens SDL Slorth 0.94917 View
ENSG00000077097 TOP2B ENSG00000136021 SCYL2 H. sapiens SDL Slorth 0.949168 View
ENSG00000077097 TOP2B ENSG00000131759 RARA H. sapiens SDL Slorth 0.949141 View
ENSG00000077097 TOP2B ENSG00000164885 CDK5 H. sapiens SDL Slorth 0.949104 View
ENSG00000077097 TOP2B ENSG00000138395 CDK15 H. sapiens SDL Slorth 0.94907 View
ENSG00000077097 TOP2B ENSG00000134686 PHC2 H. sapiens SDL Slorth 0.948986 View
ENSG00000070010 UFD1L ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.948904 View
ENSG00000077097 TOP2B ENSG00000157540 DYRK1A H. sapiens SDL Slorth 0.948895 View
ENSG00000077097 TOP2B ENSG00000102882 MAPK3 H. sapiens SDL Slorth 0.948868 View
ENSG00000077097 TOP2B ENSG00000122966 CIT H. sapiens SDL Slorth 0.94886 View
ENSG00000061938 TNK2 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.948726 View
ENSG00000077097 TOP2B ENSG00000132341 RAN H. sapiens SDL Slorth 0.948663 View
ENSG00000077097 TOP2B ENSG00000103197 TSC2 H. sapiens SDL Slorth 0.948604 View
ENSG00000077097 TOP2B ENSG00000136573 BLK H. sapiens SDL Slorth 0.948494 View
ENSG00000077097 TOP2B ENSG00000143379 SETDB1 H. sapiens SDL Slorth 0.948469 View
ENSG00000077097 TOP2B ENSG00000198793 MTOR H. sapiens SDL Slorth 0.948052 View
ENSG00000077097 TOP2B ENSG00000159259 CHAF1B H. sapiens SDL Slorth 0.947663 View
ENSG00000077097 TOP2B ENSG00000141380 SS18 H. sapiens SDL Slorth 0.947478 View
ENSG00000077097 TOP2B ENSG00000082014 SMARCD3 H. sapiens SDL Slorth 0.947446 View
ENSG00000077097 TOP2B ENSG00000156970 BUB1B H. sapiens SDL Slorth 0.947277 View
ENSG00000077097 TOP2B ENSG00000148400 NOTCH1 H. sapiens SDL Slorth 0.94727 View
ENSG00000077097 TOP2B ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.947254 View
ENSG00000077097 TOP2B ENSG00000104852 SNRNP70 H. sapiens SDL Slorth 0.946973 View
ENSG00000077097 TOP2B ENSG00000117713 ARID1A H. sapiens SDL Slorth 0.94662 View
ENSG00000077097 TOP2B ENSG00000168646 AXIN2 H. sapiens SDL Slorth 0.946575 View
ENSG00000077097 TOP2B ENSG00000141543 EIF4A3 H. sapiens SDL Slorth 0.94649 View
ENSG00000077097 TOP2B ENSG00000128512 DOCK4 H. sapiens SDL Slorth 0.946228 View
ENSG00000077097 TOP2B ENSG00000189079 ARID2 H. sapiens SDL Slorth 0.946226 View
ENSG00000077097 TOP2B ENSG00000089053 ANAPC5 H. sapiens SDL Slorth 0.946226 View
ENSG00000077097 TOP2B ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.946176 View
ENSG00000077097 TOP2B ENSG00000138468 SENP7 H. sapiens SDL Slorth 0.946176 View
ENSG00000077097 TOP2B ENSG00000143384 MCL1 H. sapiens SDL Slorth 0.946023 View
ENSG00000077097 TOP2B ENSG00000115355 CCDC88A H. sapiens SDL Slorth 0.94594 View
ENSG00000077097 TOP2B ENSG00000108094 CUL2 H. sapiens SDL Slorth 0.945909 View