TOP2B - CDC6

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
CDC6	ENSG00000094804	No diseases in record	No drugs in record	nucleotide binding protein binding ATP binding kinase binding ATPase activity GTP binding GTPase activity chromatin binding DNA replication origin binding DNA-directed DNA polymerase activity 3'-5' exonuclease activity metal ion binding 4 iron, 4 sulfur cluster binding DNA binding	CDC6 (S. cerevisiae) Cdc6 (D. melanogaster)