TOP2B - CBLB

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
CBLB	ENSG00000114423	AML	No drugs in record	phosphotyrosine residue binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding ubiquitin protein ligase activity	sli-1 (C. elegans) Cbl (D. melanogaster)