TOP2B - YWHAE

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
YWHAE	ENSG00000108953	endometrial stromal sarcoma	No drugs in record	protein binding potassium channel regulator activity enzyme binding protein domain specific binding MHC class II protein complex binding ubiquitin protein ligase binding histone deacetylase binding ion channel binding protein heterodimerization activity phosphoserine residue binding phosphoprotein binding cadherin binding involved in cell-cell adhesion	BMH1 (S. cerevisiae) BMH2 (S. cerevisiae) M117.3 (C. elegans) 14-3-3epsilon (D. melanogaster)