TOP2B

ENSG00000077097 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008301 DNA binding, bending
GO:0019899 enzyme binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
ETOPOSIDE DNA topoisomerase II inhibitor
TENIPOSIDE DNA topoisomerase II inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2 S. cerevisiae
cin-4 C. elegans
top-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077097 TOP2B ENSG00000158987 RAPGEF6 H. sapiens SDL Slorth 0.903258 View
ENSG00000077097 TOP2B ENSG00000108799 EZH1 H. sapiens SDL Slorth 0.903162 View
ENSG00000077097 TOP2B ENSG00000163041 H3F3A H. sapiens SDL Slorth 0.903093 View
ENSG00000077097 TOP2B ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.903084 View
ENSG00000077097 TOP2B ENSG00000238134 EHMT2 H. sapiens SDL Slorth 0.903064 View
ENSG00000077097 TOP2B ENSG00000099804 CDC34 H. sapiens SSL Slorth 0.903025 View
ENSG00000077097 TOP2B ENSG00000138376 BARD1 H. sapiens SSL Slorth 0.902999 View
ENSG00000077097 TOP2B ENSG00000120063 GNA13 H. sapiens SDL Slorth 0.902945 View
ENSG00000077097 TOP2B ENSG00000102054 RBBP7 H. sapiens SDL Slorth 0.902927 View
ENSG00000077097 TOP2B ENSG00000104408 EIF3E H. sapiens SDL Slorth 0.902865 View
ENSG00000077097 TOP2B ENSG00000129204 USP6 H. sapiens SDL Slorth 0.902812 View
ENSG00000077097 TOP2B ENSG00000175387 SMAD2 H. sapiens SSL Slorth 0.902709 View
ENSG00000077097 TOP2B ENSG00000131467 PSME3 H. sapiens SDL Slorth 0.9027 View
ENSG00000077097 TOP2B ENSG00000167815 PRDX2 H. sapiens SDL Slorth 0.902646 View
ENSG00000077097 TOP2B ENSG00000103126 AXIN1 H. sapiens SSL Slorth 0.902595 View
ENSG00000077097 TOP2B ENSG00000111276 CDKN1B H. sapiens SDL Slorth 0.902424 View
ENSG00000077097 TOP2B ENSG00000114166 KAT2B H. sapiens SSL Slorth 0.902275 View
ENSG00000077097 TOP2B ENSG00000135723 FHOD1 H. sapiens SDL Slorth 0.902218 View
ENSG00000077097 TOP2B ENSG00000185022 MAFF H. sapiens SDL Slorth 0.902182 View
ENSG00000060069 CTDP1 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.902135 View
ENSG00000077097 TOP2B ENSG00000215301 DDX3X H. sapiens SDL Slorth 0.902131 View
ENSG00000077097 TOP2B ENSG00000170345 FOS H. sapiens SSL Slorth 0.902073 View
ENSG00000077097 TOP2B ENSG00000169862 CTNND2 H. sapiens SDL Slorth 0.9019 View
ENSG00000077097 TOP2B ENSG00000100519 PSMC6 H. sapiens SDL Slorth 0.901818 View
ENSG00000077097 TOP2B ENSG00000213923 CSNK1E H. sapiens SDL Slorth 0.901627 View
ENSG00000062650 WAPL ENSG00000077097 TOP2B H. sapiens SDL Slorth 0.901575 View
ENSG00000077097 TOP2B ENSG00000100030 MAPK1 H. sapiens SDL Slorth 0.901345 View
ENSG00000077097 TOP2B ENSG00000130402 ACTN4 H. sapiens SDL Slorth 0.901176 View
ENSG00000077097 TOP2B ENSG00000181449 SOX2 H. sapiens SDL Slorth 0.901025 View
ENSG00000074319 TSG101 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.900882 View
ENSG00000077097 TOP2B ENSG00000134308 YWHAQ H. sapiens SDL Slorth 0.90083 View
ENSG00000077097 TOP2B ENSG00000173404 INSM1 H. sapiens SDL Slorth 0.900763 View
ENSG00000077097 TOP2B ENSG00000168148 HIST3H3 H. sapiens SSL Slorth 0.900753 View
ENSG00000077097 TOP2B ENSG00000152669 CCNO H. sapiens SDL Slorth 0.900734 View
ENSG00000077097 TOP2B ENSG00000114062 UBE3A H. sapiens SSL Slorth 0.900587 View
ENSG00000077097 TOP2B ENSG00000158290 CUL4B H. sapiens SDL Slorth 0.900579 View
ENSG00000077097 TOP2B ENSG00000165392 WRN H. sapiens SSL Slorth 0.900306 View
ENSG00000077097 TOP2B ENSG00000109320 NFKB1 H. sapiens SSL Slorth 0.900151 View
ENSG00000077097 TOP2B ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.900033 View
ENSG00000077097 TOP2B ENSG00000177889 UBE2N H. sapiens SSL Slorth 0.89967 View