TOP2B

ENSG00000077097 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008301 DNA binding, bending
GO:0019899 enzyme binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
ETOPOSIDE DNA topoisomerase II inhibitor
TENIPOSIDE DNA topoisomerase II inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2 S. cerevisiae
cin-4 C. elegans
top-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077097 TOP2B ENSG00000186153 WWOX H. sapiens SDL Slorth 0.911964 View
ENSG00000077097 TOP2B ENSG00000225830 ERCC6 H. sapiens SDL Slorth 0.911854 View
ENSG00000077097 TOP2B ENSG00000094916 CBX5 H. sapiens SDL Slorth 0.911775 View
ENSG00000077097 TOP2B ENSG00000137825 ITPKA H. sapiens SDL Slorth 0.911732 View
ENSG00000077097 TOP2B ENSG00000136807 CDK9 H. sapiens SSL Slorth 0.911638 View
ENSG00000077097 TOP2B ENSG00000101367 MAPRE1 H. sapiens SDL Slorth 0.911604 View
ENSG00000077097 TOP2B ENSG00000116675 DNAJC6 H. sapiens SDL Slorth 0.911552 View
ENSG00000077097 TOP2B ENSG00000141738 GRB7 H. sapiens SDL Slorth 0.911398 View
ENSG00000077097 TOP2B ENSG00000149554 CHEK1 H. sapiens SSL Slorth 0.911384 View
ENSG00000077097 TOP2B ENSG00000119048 UBE2B H. sapiens SSL Slorth 0.911218 View
ENSG00000077097 TOP2B ENSG00000105656 ELL H. sapiens SDL Slorth 0.911054 View
ENSG00000077097 TOP2B ENSG00000078140 UBE2K H. sapiens SDL Slorth 0.911054 View
ENSG00000077097 TOP2B ENSG00000159210 SNF8 H. sapiens SDL Slorth 0.911039 View
ENSG00000077097 TOP2B ENSG00000163625 WDFY3 H. sapiens SDL Slorth 0.910728 View
ENSG00000077097 TOP2B ENSG00000100644 HIF1A H. sapiens SDL Slorth 0.910711 View
ENSG00000077097 TOP2B ENSG00000175054 ATR H. sapiens SDL Slorth 0.910468 View
ENSG00000077097 TOP2B ENSG00000163939 PBRM1 H. sapiens SDL Slorth 0.910439 View
ENSG00000077097 TOP2B ENSG00000108443 RPS6KB1 H. sapiens SSL Slorth 0.9102 View
ENSG00000077097 TOP2B ENSG00000118007 STAG1 H. sapiens SDL Slorth 0.910055 View
ENSG00000077097 TOP2B ENSG00000171791 BCL2 H. sapiens SDL Slorth 0.910045 View
ENSG00000077097 TOP2B ENSG00000139687 RB1 H. sapiens SDL Slorth 0.909845 View
ENSG00000067606 PRKCZ ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.909732 View
ENSG00000077097 TOP2B ENSG00000136238 RAC1 H. sapiens SDL Slorth 0.909657 View
ENSG00000077097 TOP2B ENSG00000187741 FANCA H. sapiens SDL Slorth 0.909653 View
ENSG00000077097 TOP2B ENSG00000147416 ATP6V1B2 H. sapiens SDL Slorth 0.909422 View
ENSG00000077097 TOP2B ENSG00000100320 RBFOX2 H. sapiens SDL Slorth 0.909348 View
ENSG00000077097 TOP2B ENSG00000157601 MX1 H. sapiens SDL Slorth 0.909326 View
ENSG00000077097 TOP2B ENSG00000196911 KPNA5 H. sapiens SDL Slorth 0.908974 View
ENSG00000077097 TOP2B ENSG00000153561 RMND5A H. sapiens SDL Slorth 0.908908 View
ENSG00000077097 TOP2B ENSG00000129514 FOXA1 H. sapiens SDL Slorth 0.908881 View
ENSG00000077097 TOP2B ENSG00000125834 STK35 H. sapiens SDL Slorth 0.908869 View
ENSG00000077097 TOP2B ENSG00000142875 PRKACB H. sapiens SDL Slorth 0.908791 View
ENSG00000077097 TOP2B ENSG00000175643 RMI2 H. sapiens SDL Slorth 0.908705 View
ENSG00000077097 TOP2B ENSG00000166226 CCT2 H. sapiens SDL Slorth 0.908569 View
ENSG00000077097 TOP2B ENSG00000143776 CDC42BPA H. sapiens SDL Slorth 0.908487 View
ENSG00000077097 TOP2B ENSG00000166477 LEO1 H. sapiens SDL Slorth 0.9084 View
ENSG00000077097 TOP2B ENSG00000122565 CBX3 H. sapiens SDL Slorth 0.908279 View
ENSG00000077097 TOP2B ENSG00000177688 SUMO4 H. sapiens SDL Slorth 0.908265 View
ENSG00000077097 TOP2B ENSG00000160201 U2AF1 H. sapiens SDL Slorth 0.908255 View
ENSG00000077097 TOP2B ENSG00000169714 CNBP H. sapiens SDL Slorth 0.907971 View