TOP2B

ENSG00000077097 - H. sapiens

Pathways

Go term Description
GO:0003682 chromatin binding
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005080 protein kinase C binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0008301 DNA binding, bending
GO:0019899 enzyme binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity

Drugs

Drug name Description
ETOPOSIDE DNA topoisomerase II inhibitor
TENIPOSIDE DNA topoisomerase II inhibitor

Diseases

No diseases in record

Orthologs

Gene Organism
TOP2 S. cerevisiae
cin-4 C. elegans
top-2 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000077097 TOP2B ENSG00000100722 ZC3H14 H. sapiens SDL Slorth 0.918729 View
ENSG00000077097 TOP2B ENSG00000164104 HMGB2 H. sapiens SDL Slorth 0.91872 View
ENSG00000077097 TOP2B ENSG00000147133 TAF1 H. sapiens SDL Slorth 0.918688 View
ENSG00000077097 TOP2B ENSG00000197579 TOPORS H. sapiens SDL Slorth 0.91864 View
ENSG00000073584 SMARCE1 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.918633 View
ENSG00000077097 TOP2B ENSG00000127445 PIN1 H. sapiens SDL Slorth 0.918402 View
ENSG00000077097 TOP2B ENSG00000137486 ARRB1 H. sapiens SDL Slorth 0.918116 View
ENSG00000077097 TOP2B ENSG00000137841 PLCB2 H. sapiens SDL Slorth 0.917876 View
ENSG00000077097 TOP2B ENSG00000129911 KLF16 H. sapiens SDL Slorth 0.91777 View
ENSG00000077097 TOP2B ENSG00000139613 SMARCC2 H. sapiens SDL Slorth 0.917751 View
ENSG00000077097 TOP2B ENSG00000196961 AP2A1 H. sapiens SDL Slorth 0.917621 View
ENSG00000077097 TOP2B ENSG00000135945 REV1 H. sapiens SDL Slorth 0.917521 View
ENSG00000072062 PRKACA ENSG00000077097 TOP2B H. sapiens SDL Slorth 0.917367 View
ENSG00000077097 TOP2B ENSG00000178573 MAF H. sapiens SDL Slorth 0.917216 View
ENSG00000077097 TOP2B ENSG00000134954 ETS1 H. sapiens SDL Slorth 0.917156 View
ENSG00000077097 TOP2B ENSG00000103479 RBL2 H. sapiens SDL Slorth 0.917055 View
ENSG00000077097 TOP2B ENSG00000154016 GRAP H. sapiens SDL Slorth 0.916963 View
ENSG00000064012 CASP8 ENSG00000077097 TOP2B H. sapiens SDL Slorth 0.916944 View
ENSG00000077097 TOP2B ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.916933 View
ENSG00000077097 TOP2B ENSG00000126561 STAT5A H. sapiens SDL Slorth 0.916826 View
ENSG00000077097 TOP2B ENSG00000122779 TRIM24 H. sapiens SDL Slorth 0.916619 View
ENSG00000077097 TOP2B ENSG00000078140 UBE2K H. sapiens SSL Slorth 0.916507 View
ENSG00000077097 TOP2B ENSG00000079102 RUNX1T1 H. sapiens SDL Slorth 0.916439 View
ENSG00000077097 TOP2B ENSG00000165115 KIF27 H. sapiens SDL Slorth 0.916209 View
ENSG00000077097 TOP2B ENSG00000172367 PDZD3 H. sapiens SDL Slorth 0.916209 View
ENSG00000077097 TOP2B ENSG00000163132 MSX1 H. sapiens SDL Slorth 0.916133 View
ENSG00000077097 TOP2B ENSG00000134057 CCNB1 H. sapiens SDL Slorth 0.916023 View
ENSG00000077097 TOP2B ENSG00000173801 JUP H. sapiens SDL Slorth 0.91602 View
ENSG00000077097 TOP2B ENSG00000170734 POLH H. sapiens SDL Slorth 0.915755 View
ENSG00000077097 TOP2B ENSG00000154237 LRRK1 H. sapiens SDL Slorth 0.915728 View
ENSG00000077097 TOP2B ENSG00000185345 PARK2 H. sapiens SDL Slorth 0.915725 View
ENSG00000077097 TOP2B ENSG00000126215 XRCC3 H. sapiens SDL Slorth 0.915643 View
ENSG00000004487 KDM1A ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.915574 View
ENSG00000077097 TOP2B ENSG00000119772 DNMT3A H. sapiens SDL Slorth 0.915568 View
ENSG00000077097 TOP2B ENSG00000124486 USP9X H. sapiens SDL Slorth 0.915554 View
ENSG00000010810 FYN ENSG00000077097 TOP2B H. sapiens SDL Slorth 0.915547 View
ENSG00000077097 TOP2B ENSG00000082258 CCNT2 H. sapiens SDL Slorth 0.915343 View
ENSG00000077097 TOP2B ENSG00000166483 WEE1 H. sapiens SSL Slorth 0.915327 View
ENSG00000044574 HSPA5 ENSG00000077097 TOP2B H. sapiens SSL Slorth 0.915261 View
ENSG00000077097 TOP2B ENSG00000124535 WRNIP1 H. sapiens SDL Slorth 0.91526 View