TOP2B - JUP

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
JUP	ENSG00000173801	No diseases in record	No drugs in record	transcription coactivator activity signal transducer activity structural molecule activity structural constituent of cell wall protein binding protein kinase binding protein phosphatase binding protein homodimerization activity alpha-catenin binding cadherin binding cell adhesion molecule binding cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication cadherin binding involved in cell-cell adhesion	bar-1 (C. elegans) hmp-2 (C. elegans) arm (D. melanogaster)