TOP2B - PBRM1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
PBRM1	ENSG00000163939	clear cell renal carcinoma breast	No drugs in record	DNA binding chromatin binding protein binding	RSC1 (S. cerevisiae) RSC2 (S. cerevisiae) pbrm-1 (C. elegans) polybromo (D. melanogaster)