BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000157764 BRAF ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.95617 View
ENSG00000109332 UBE2D3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.956107 View
ENSG00000157764 BRAF ENSG00000164109 MAD2L1 H. sapiens SSL Slorth 0.956062 View
ENSG00000157764 BRAF ENSG00000163098 BIRC8 H. sapiens SDL Slorth 0.95605 View
ENSG00000157764 BRAF ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.955991 View
ENSG00000157764 BRAF ENSG00000198561 CTNND1 H. sapiens SSL Slorth 0.95569 View
ENSG00000157764 BRAF ENSG00000169032 MAP2K1 H. sapiens SDL Slorth 0.955687 View
ENSG00000118260 CREB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.955636 View
ENSG00000157764 BRAF ENSG00000174775 HRAS H. sapiens SDL Slorth 0.955583 View
ENSG00000157764 BRAF ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.955524 View
ENSG00000126261 UBA2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.955465 View
ENSG00000157764 BRAF ENSG00000172936 MYD88 H. sapiens SSL Slorth 0.955403 View
ENSG00000089159 PXN ENSG00000157764 BRAF H. sapiens SDL Slorth 0.955397 View
ENSG00000110395 CBL ENSG00000157764 BRAF H. sapiens SDL Slorth 0.95536 View
ENSG00000157764 BRAF ENSG00000165806 CASP7 H. sapiens SSL Slorth 0.955264 View
ENSG00000147010 SH3KBP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.955186 View
ENSG00000079999 KEAP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.955084 View
ENSG00000157764 BRAF ENSG00000283094 PTEN H. sapiens SSL Slorth 0.955047 View
ENSG00000055332 EIF2AK2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.95495 View
ENSG00000157764 BRAF ENSG00000172534 HCFC1 H. sapiens SSL Slorth 0.954859 View
ENSG00000157764 BRAF ENSG00000171608 PIK3CD H. sapiens SDL Slorth 0.954848 View
ENSG00000097007 ABL1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.954807 View
ENSG00000112531 QKI ENSG00000157764 BRAF H. sapiens SSL Slorth 0.954787 View
ENSG00000106355 LSM5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.95473 View
ENSG00000101343 CRNKL1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.954623 View
ENSG00000100906 NFKBIA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.954461 View
ENSG00000071564 TCF3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.954435 View
ENSG00000106290 TAF6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.954367 View
ENSG00000130726 TRIM28 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.954315 View
ENSG00000119541 VPS4B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.95418 View
ENSG00000072518 MARK2 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.954108 View
ENSG00000157764 BRAF ENSG00000165280 VCP H. sapiens SSL Slorth 0.954023 View
ENSG00000100603 SNW1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.953903 View
ENSG00000118046 STK11 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.953797 View
ENSG00000117676 RPS6KA1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.953725 View
ENSG00000090372 STRN4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.953673 View
ENSG00000150093 ITGB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.953619 View
ENSG00000051180 RAD51 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.953534 View
ENSG00000128739 SNRPN ENSG00000157764 BRAF H. sapiens SSL Slorth 0.953462 View
ENSG00000157764 BRAF ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.953198 View