BRAF

ENSG00000157764 - H. sapiens

Pathways

Go term Description
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004709 MAP kinase kinase kinase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
GO:0031267 small GTPase binding

Drugs

Drug name Description
DABRAFENIB Serine/threonine-protein kinase B-raf inhibitor
REGORAFENIB Tyrosine-protein kinase ABL inhibitor
SORAFENIB Serine/threonine-protein kinase RAF inhibitor
VEMURAFENIB Serine/threonine-protein kinase B-raf inhibitor

Diseases

Disease Name
melanoma
colorectal
papillary thyroid
borderline ovarian
NSCLC
cholangiocarcinoma
pilocytic astrocytoma
Spitzoid tumour
pancreas acinar carcinoma
melanocytic nevus
prostate
gastric

Orthologs

Gene Organism
lin-45 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000141027 NCOR1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959767 View
ENSG00000157764 BRAF ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.959748 View
ENSG00000096384 HSP90AB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.95973 View
ENSG00000001626 CFTR ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959577 View
ENSG00000112118 MCM3 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959442 View
ENSG00000149311 ATM ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959377 View
ENSG00000087586 AURKA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959368 View
ENSG00000109971 HSPA8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959324 View
ENSG00000078140 UBE2K ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959251 View
ENSG00000157764 BRAF ENSG00000171435 KSR2 H. sapiens SDL Slorth 0.959186 View
ENSG00000149273 RPS3 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.959177 View
ENSG00000149136 SSRP1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959009 View
ENSG00000148835 TAF5 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.959009 View
ENSG00000108424 KPNB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.958871 View
ENSG00000157764 BRAF ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.958829 View
ENSG00000002016 RAD52 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.958642 View
ENSG00000157764 BRAF ENSG00000198793 MTOR H. sapiens SDL Slorth 0.958592 View
ENSG00000127511 SIN3B ENSG00000157764 BRAF H. sapiens SSL Slorth 0.958588 View
ENSG00000157764 BRAF ENSG00000169375 SIN3A H. sapiens SSL Slorth 0.95854 View
ENSG00000105810 CDK6 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.958517 View
ENSG00000139687 RB1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.958403 View
ENSG00000105568 PPP2R1A ENSG00000157764 BRAF H. sapiens SSL Slorth 0.958349 View
ENSG00000157764 BRAF ENSG00000167552 TUBA1A H. sapiens SSL Slorth 0.958177 View
ENSG00000073969 NSF ENSG00000157764 BRAF H. sapiens SSL Slorth 0.958097 View
ENSG00000136936 XPA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.957943 View
ENSG00000157764 BRAF ENSG00000169047 IRS1 H. sapiens SSL Slorth 0.957748 View
ENSG00000157764 BRAF ENSG00000176720 BOK H. sapiens SDL Slorth 0.957688 View
ENSG00000062822 POLD1 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.957659 View
ENSG00000132646 PCNA ENSG00000157764 BRAF H. sapiens SSL Slorth 0.957612 View
ENSG00000134308 YWHAQ ENSG00000157764 BRAF H. sapiens SSL Slorth 0.95752 View
ENSG00000157764 BRAF ENSG00000163743 RCHY1 H. sapiens SSL Slorth 0.957332 View
ENSG00000064012 CASP8 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.957135 View
ENSG00000108953 YWHAE ENSG00000157764 BRAF H. sapiens SSL Slorth 0.956926 View
ENSG00000141564 RPTOR ENSG00000157764 BRAF H. sapiens SSL Slorth 0.956821 View
ENSG00000157764 BRAF ENSG00000180176 TH H. sapiens SDL Slorth 0.956747 View
ENSG00000080815 PSEN1 ENSG00000157764 BRAF H. sapiens SDL Slorth 0.956742 View
ENSG00000142192 APP ENSG00000157764 BRAF H. sapiens SSL Slorth 0.956695 View
ENSG00000157764 BRAF ENSG00000163930 BAP1 H. sapiens SSL Slorth 0.956695 View
ENSG00000147536 GINS4 ENSG00000157764 BRAF H. sapiens SSL Slorth 0.956274 View
ENSG00000151247 EIF4E ENSG00000157764 BRAF H. sapiens SSL Slorth 0.956254 View